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Yıl:2016; Cilt: 19; Sayı: 4>> Özet
TAM METİN
Klinik Psikiyatri Dergisi; 2016;19(4):211-214
Esrar Kullanımına Bağlı Gelişen Amotivasyonel Sendrom: Testosteron Ekleme Tedavisiyle Belirtileri Düzelen Bir Olgu Sunumu
S Ekinci, HU Kural
Fransız Lape Hastanesi
Esrar, cannabis sativa adlı bitkinin tohumlarından ve kurutulmuş yapraklarından elde edilir, keyif verici etkisi nedeniyle dünyada yaygın olarak kullanılmaktadır. Yapılan epidemiyolojik çalışmalarda, en az bir kez esrar kullanımı ülkeler arasında büyük farklılıklar göstermektedir. İngiltere’de %41, Danimarka %17, Macaristan %6, Türkiye’de %1.2-4 kullanım oranları belirlenmiştir. Esrar kullanım bozukluklarının, klinik sınıflandırılması ve tedavisiyle ilgili bir çok çalışma yapılmıştır. Esrar kullanımına bağlı gelişen amotivasyonel sendrom ise klinik olarak az bilinmekte ve tedavisi ile ilgili günümüzde çok az klinik çalışma bulunmaktadır. Amotivasyonel sendrom, kronik esrar kullanımı ile ortaya çıkan; enerjide azalma, motivasyon düşüklüğü, sosyal etkileşimsizlik, duygulanımda küntleşme, amaca yönelik aktivitelerde azalma, zayıf muhakeme, konsantrasyon eksikliği, bellek kusuru gibi bilişsel ve duygusal fonksiyonlarda bozulmayla seyreden bir sendromdur. Yapılan çalışmalarda, kronik esrar kullanım bozukluğu olanlarda, motivasyon düşüklüğü, enerji azlığı gibi amotivasyonel sendrom klinik belirtileri %16-21 oranında görülmekte buna rağmen amotivasyonel sendrom, az tanı konulan, ayrıcı tanısı ve tedavisi konusunda çok az çalışmaların olduğu bir klinik tablo olarak karşımıza çıkmaktadır. Tedavisinde, öncelikle altta yatan nedenin ortadan kaldırılması, esrar kullanımı varsa bırakılması önerilmektedir. Bu yazıda, kronik esrar kullanımı sonucu amtoivasyonel sendrom gelişen bir olguda, testosteron ekleme tedavisiyle, klinik belirtilerinde düzelme gözlenen bir olgu sunulmaktadır.
Amotivational Syndrome Caused by Cannabis Use: A Case Who Improved with Additional Testosterone Combination Treatment
Cannabis which is obtained from seeds and dried leaves of the cannabis sativa plant is widely used in the world due to its recreational effect. Epidemiological studies were suggested huge differences among countries in terms of using cannabis at least once. The percentiles of use for countries were determined as 41% in England, 17% in Denmark, 6% in Hungary, and 1.2-4% in Turkey. Lots of studies about cannabis use disorders, clinical classification, and treatment were conducted. However, amotivational syndrome caused by cannabis use is not only a clinically less known phenomenon but also we have limited clinical experience about this syndrome. Amotivational syndrome is a syndrome which is caused by cannabis use and which goes along with the cognitive and emotional dysfunctions such as decrease in energy and motivation, lack of social interaction, apathy, decrease in goal-oriented activities, poor judgement, lack of concentration, and memory problems. In studies, it was shown that clinical symptoms of motivational syndrome such as decrease in motivation and energy in 16- 21% of people with cannabis use disorder was observed but motivational syndrome emerges as a clinical phenomenon which has been diagnosed less and we have a few studies about definitive diagnosis and treatment. For treatment, it is recommended that underlying problem should be eliminated and that cannabis use should be stopped.. In this article, a case which had amotivational syndrome caused by cannabis use and which had a recovery in clinical symptoms with the treatment of adding testosterone.

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