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Yıl:2016; Cilt: 2; Sayı: 1>> Özet
Türkiye Klinikleri Çocuk Psikiyatrisi Özel Dergisi; 2016;2(1):25-36
Çocuk ve Ergen Başlangıçlı Bipolar Bozukluğun Farmakolojik Tedavisi
NC Binici, Nİ Emiroğlu
Dr.Behçet Uz Çocuk Hastalıkları ve Cerrahisi Eğitim ve Araştırma Hastanesi, İzmir
Çocuk ve ergenlik başlangıçlı bipolar bozukluk, erişkin bipolar bozukluğa göre işlevsellikte daha ciddi bozulmalara neden olmaktadır. Tanı koymakla ilgili zorluklar tedaviye başlama süresini geciktirmekte ve uygun tedavi seçiminin yapılamaması gidişatı olumsuz etkilemektedir. Aynı zamanda bu yaş grubunun özelliklerinden dolayı tedavi uyumu ile ilgili problemlere daha sık rastlanmaktadır. Akut dönem tedavilerinde atipik antibiyotiklerin, duygudurum düzenleyicilere üstünlüğü görünmekle beraber, metabolik yan etkiler çok daha sık bildirilmektedir. Tedavi seçiminde bu ilaçların yan etkileri, tedavi uyumu ve ilaç maliyetleri göz önüne alınarak, bu yararlı ve hızlı etkilerinin kar-zarar hesabının yapılması önemli ve gerekli görülmektedir. Bu gözden geçirmede çocukluk ve ergenlik başlangıçlı bipolar bozuklukta tedavi yaklaşımları ele alınmıştır.
Pharmacotherapy of Child and Adolescent Onset Bipolar Disorder
Child and adolescent onset bipolar disorder causes more severe impairment on functionality than adult bipolar disorder. Dilemma in diagnose brings longer duration of time to start treatment and also causes confusion in choosing appropriate medication that effects prognosis negatively. Meanwhile treatment compliance is a problematic issue due to the features of this age group. Although atypic antipsychotics are more effective than mood stabilizers in the treatment of acute phases of disorder, metabolic side effects are more often. While deciding medication, besides this fast and effective response, it is important and necessary to consider the side effects, treatment compliance and cost of medication. In this review, we discuss pharmacological treatment approaches of child and adolescent onset bipolar disorder.

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