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Yıl:2016; Cilt: 3; Sayı: 2>> Özet
TAM METİN
The Journal of Neurobehavioral Sciences; 2016;3(2):86-88
Yapay Görme Kaybında İşlevsel MR Görüntüleme
AA Antonio-Santos, ER Eggenberger, DC Zhu
Michigan State University, Michigan
Tek denekli bu çalışma, normal görme durumuyla yanıltıcı görme kaybı ve yapay-refraktif bulanıklık durumunu ayırt etmek için fonksiyonel magnetik resonans görünteleme(fMRI) kullanmıştır. Normal binoküler görüş durumunda, parietooksipital alanının aktivasyonu görme yolunda kan oksijenizasyonu bağımlılık düzeyi(BOLD) sinyallerinin normal örneklerini yansıtmıştır. Yanıltıcı/ fonksiyonel görme kaybı ve yapay-refraktif bulanıklık durumu esnasında parietooksipital görme yolunda hipoaktivasyon vardı. Bu çalışma göstermiştir ki; denek, fMRI sonuçlarını ciddi derecede etkileyebilir. Bu nedenle, bireysel fonksiyonel hastalarda güvenilir bir şekilde kliniksel bir teşhis aracı olarak hizmet etmesi için fMRI kullanımının yükseltilmesi amacıyla daha fazla araştırma ve protokol gelişimine ihtiyaç duyulmuştur
Functional MRI in Feigned Visual Loss
This single-subject study studied the ability of functional magnetic resonance imaging (fMRI) to discern normal visual condition compared to feigned visual loss and induced-refractive blur condition. Under the normal binocular vision condition, activation of the parieto-occipital area reflected normal patterns of blood oxygenation level-dependent (BOLD) signals in the visual pathway. During the feigned/functional visual loss and refractive-induced blur condition, there was hypoactivation in the parieto-occipital visual pathway. This study showed that the subject could strongly influence the fMRI results, thus, further investigation and protocol refinement are needed to maximize the ability of fMRI to reliably serve as a clinical diagnostic tool in individual functional patients.

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