Dergi Ara >>
Yıl:2016; Cilt: 9; Sayı: 2>> Özet
Türkiye Klinikleri Psikiyatri Özel Dergisi; 2016;9(2):38-45
Alkol Kullanım Bozuklukları ve Klinik Biyokimyasal Belirteçler
DG Öyeçkin
Çanakkale Onsekiz Mart Üniversitesi, Çanakkale
Alkol kullanım bozukluklarının tanı, tedavi ve izleminde biyokimyasal incelemeler gereklidir. Bu beyin hastalığında vasküler, kardiyak, metabolik ve nörolojik birçok komplikasyon gelişir. Bu alanda kullanılacak olan biyokimyasal belirteçlerin hem hastalığın kliniğini, şiddetini doğru tanıması, tedavi süreci, izlem ve adli uygulamalarda güvenilir ve geçerli olması, ayrıca hastalığa bağlı oluşabilecek komplikasyonları da öngörmesi beklenir. Geleneksel biyokimyasal incelemeler ağırlıklı olarak kullanılmakta yanı sıra birçok yeni aday molekül de tanımlanmaktadır. İdeale yakın bir yöntemin geliştirilmesi çok yönlü ve çoğul bir patogenezi olan bu hastalık için pek mümkün görünmese de elimizde var olan yöntemlerin uygun şekilde kullanılması klinisyenler için yol gösterici olacaktır. Gelecekte yeni teknolojiler ile geliştirecek olan yeni moleküller ise bizler için umut vericidir.
Alcohol Use Disorders and Biomarkers
The biochemical tests are required for the treatment, monitoring and the diagnosis of alcohol use disorders.Vascular, cardiac, metabolic, and neurological complications occur in this brain disease. The biological markers must diagnose the clinical features correctly, monitore the treatment, predict the complications and be reliable on forensic applications.Traditional biomarkers are mostly used and new biomarkers are also described. But it is unlikely to develop an ideal method because of the multi-faceted pathogenesis of the disease however the conventional methods can be appropriately used. There is new developing technologies and molecules which have promising features.

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