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Yıl:2015; Cilt: 1; Sayı: 3>> Özet
Türkiye Klinikleri Çocuk Psikiyatrisi Özel Dergisi; 2015;1(3):6-16
Erken Başlangıçlı Şizofrenide Prodromal Dönem ve Klinik Özellikleri
Ö Yalçın
Bakırköy Prof. Dr. Mazhar Osman Ruh Sağlığı ve Sinir Hastalıkları Eğitim ve Araştırma Hastanesi, İstanbul
Psikotik bozukluklarda prodromal dönem, kişinin davranış ve yaşantılarında ilk sapmanın olduğu dönem ile ilk açık psikotik bozukluk arasında geçen zamandır. Sıklıkla erken dönemde silik negatif, afektif ve nevrotik bulgularla, geç dönemde ise daha belirgin pozitif bulgularla karakterize olabilir. Prodromal dönemde olduğu düşünülen her bireyde psikotik bozukluk gelişmez. Bu dönemde tedavi uygulanmasıyla ilişkili görüş ayrılıkları mevcuttur. Bu dönemde bilişsel davranışçı terapi, omega-3 yağ asitleri, seçici serotonin geri alım inhibitörleri ve özellikle de geç prodromal dönemde atipik antipsikotikler kullanılabilmektedir. Psikotik bozuklukların önceden tahmin edilebilmesi ve müdahale edilebilmesine yönelik daha çok araştırmaya ihtiyaç vardır.
Prodromal Phase in Early Onset Schizophrenia and Clinical Features
Prodomal phase in psychotic disorders may be described as a period between first frank psychotic episode and first observed deviant behaviors and experiences in an individual. This period is frequently characterized as attenuated negative, affective and neurotic symptoms in early stages and more prominent positive symptoms in late stages. Patients who are accepted as in prodromal stage do not always develop psychotic disorders. There are controversy about treating patients in this period. In this stage cognitive behavioral therapy, omega-3 fatty acids, selective serotonin reuptake inhibitors and particullarly in late stages atypical antipsycotics can be used. There is a need of future studies aiming to predict and to intervene patients before developing psychotic disorders.

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