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Yıl:2016; Cilt: 6; Sayı: 2>> Özet
TAM METİN
Journal of Mood Disorders; 2016;6(2):54-62
Factors associated with depression in patients with schizophrenia
G Balcı, GB Öter, HA Akdağ, A Bekki, C Kısa, E Göka
Birecik Devlet Hastanesi, Şanlıurfa
Amaç: Bu çalışmada, Mental Bozuklukların Tanısal ve Sayımsal El Kitabı’na (Diagnostic and Statistical Manual of Mental Disorders -DSM5) göre şizofreni tanısı almış hastalarda depresyon yaygınlığının saptanması, depresyonla ilişkili sosyodemografik faktörlerin belirlenmesi, şizofrenideki depresyonun pozitif ve negatif belirtileriyle antipsikotik ilaçların yan etkileri ve içgörü ilişkisinin araştı- rılması amaçlanmıştır. Yöntem: Rastgele seçilen 120 şizofreni hastası sosyodemografik özellikleri ve elde edilen pozitif-negatif belirtiler, şizofrenide depresyon, ekstrapiramidal belirtiler ve içgörü değerlendirme ölçek skorları bakımından incelenmiştir. Bulgular: Bu çalışmada şizofrenide depresyon görülme oranı %42.5 bulunmuştur. Şizofrenide görülen depresyonun düşük sosyoekonomik durum, ailede psikoz öyküsü ve ailede iki uçlu bozukluk öyküsünün varlığı, hastada intihar girişimi öyküsü ve tedavisiz kalınan süre ile ilişkili olduğu saptanmıştır. Ayrıca varsanılar ve sanrılar alt ölçeği, duygulanımda düzleşme, aloji, avolüsyon, apati ve dikkat alt ölçekleri, parkinsonizm alt ölçeği ve içgörü düzeyi ile depresyonun doğrudan ilişkili olduğu da belirlenmiştir. Sonuç: İlişkili sosyodemografik faktörlerin incelenmesi depresyon belirlenmesinde yardımcıdır ve depresyon, şizofreninin tüm evrelerine eşlik edebilir. Sonuç olarak depresyon şizofreninin temel göstergelerinden biri olabilir.
Şizofreni hastalarında görülen depresyonla ilişkili faktörler
Objective: In this study, it is aimed to determine the prevalence of depression rate, socio-demographic factors related to depression and to determine the relationship between depression in schizophrenia with positive and negative symptoms, insight and antipsychotics drugs’ side effects in patients with a diagnosis of schizophrenia according to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Method: Randomly selected 120 schizophrenia patients are examined regarding socio-demographic characteristics, obtained positive and negative symptoms, depression in schizophrenia, extrapyramidal symptoms, and insight scale scores. Results: Depression rate in schizophrenia is found as 42.5%. Depression is related to low socioeconomic status, family history of psychosis and affective disorders, patients’ suicide history and run-in period. Also, hallucinations and delusions sub-scales, flattening, alogia, apathy and attention sub-scales, Parkinsonism sub-scale and insight levels are found directly related to depression. Conclusions: Examining related sociodemographic factors can aid in determining depression and depression may accompany all the phases of schizophrenia. Therefore, it can be one of the basic indications of schizophrenia.

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