Dergi Ara >>
Yıl:1997; Cilt: 35; Sayı: 1>> Özet
TAM METİN
Yeni Symposium; 1997;35(1):33-39
Parkinson hastalığında mental fonksiyonların beyin biyoelektrisitesi ile ilişkisi
H Apaydın, S Özekmekçi, N Yeni, K Tombul, N Karaağaç
İ.Ü. Cerrahpaşa Tıp Fak. Nöroloji Anabilim Dalı
Bu çalışmada 51 Parkinson hastasının kognitif fonksiyonları, depresyon varlığı, motor ve kognitif fonksiyonlardaki
değişikliklerin EEG üzerine ne şekilde yansıdığı araştırıldı ve yaşları uygun 46 kontrol ile kıyaslandı.
Kognitif fonksiyonları saptamak için kısa mental durum testi (KMT), depresyon varlığını araştırmak amacıyla
lung depresyon ölçeği uygulandı. KMT verileri hasta ve kontrol gruplarında farklı bulunmadı. Ancak
öğrenme ve hatırlama fonksiyonları kontrol grubuna kıyasla aksamış bulundu. lung testinde hastaların
%50'sinde depresyon varlığı saptandı.
Çalışmaya alınan hastalar arasından 25 Parkinson hastasına EEG tetkiki yapıldı. 18 hastada EEG normaldi,
Tsinde ise patolojik bulgular saptandı. EEG'de patoloji saptanan 7 hastanın kognitif fonksiyonlarının
normalolmakla birlikte, anlamlı olarak daha ileri yaşta oldukları, hastalığın geç yaşta başladığı. hastalık
süresinin daha uzun ve motor semptomların daha ağır olduğu belirlendi. Patolojik EEG bulgusu gösteren
ve göstermeyen hastaların levodopa kullanma süresi ve dozu yönünden farklılık gözlenmedi.
The relationship between mental functions in Parkinson disease and brain bioelectricity
As the first part of this study, evaluation of mental status and the presence of depression in 51 patients
with Parkinson's disease (PO) were evaluated and compared with those of 46 control~ by using respectively
the short test of mental status (STMS) and lung depression scale.
As the second part, effect of alterations in motor and cognitive functions on EEG were investigated in 25
patients with PO. STMS total score were not statistically different between patients and controls. But,
among subset items of STMS, immediate recall (Iearning) and recall were found to be disturbed in patients
compared with controls. 50% of patients expressed depression in lung scale.
Several abnormalities in EEG recordings were found in 7 patients who were significantly older, whose ageonset
of PO were later, disease duration were longer and motor symptoms were more disturbed than
those of the remainder patients (n=18). Patients with and without abnormalities in EEG did not show any
differences in dose and duration of levodopa therapy.

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