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Yıl:2015; Cilt: 53; Sayı: 4>> Özet
TAM METİN
Yeni Symposium; 2015;53(4):33-36
Tip-1 Diyabetes Mellituslu Bir Çocukta Aripiprazol Kullanımına Bağlı Gelişen Hiperglisemi: Olgu Sunumu
M Küçükköse, BK Başay
Aydın Devlet Hastanesi, Aydın
Atipik antipsikotiklerin kilo artışı, insülin direnci, dislipidemi ve tip 2 diyabet gibi birçok metabolik sorunlara neden olduğu bilinmektedir. Yeni bir antipsikotik olan aripiprazol; kilo, glikoz toleransı ve prolaktin düzeyi üzerindeki etkisi diğer antipsikotiklerle karşılaş- tırıldığında daha güvenli bir profile sahiptir. Ancak son yıllarda aripiprazol kullanımına bağlı olarak birkaç olguda hiperglisemi ve diyabetik ketoasidoz geliştiğini bildiren sunumlar bulunmaktadır. Bu olgu sunumunda, aripiprazol kullanımına bağlı olarak hiperglisemi gelişen tip 1 diyabetes mellituslu (DM) bir olgu literatür ışığında tartışılmıştır.
Aripiprazole Induced Hyperglycemia in A Child with Tip 1 Diabetes Mellitus: A Case Report
Atypical antipsychotics is known to cause a number of adverse metabolic effects, including weight gain, insulin resistance, hyperglycemia, dyslipidemia and type 2 diabetes mellitus. Aripiprazole is an new atypical antipsychotic that has a safer profile compared to other antipsychotic medications with regard to its effect on weight gain, glucose tolerance and prolactin level. However, recently there have been few case reports on hiperglisemia and diabetic ketoacidosis related by aripiprazole. In this report, we discuss a clinical case with tip 1 diabetes mellitus that developed hiperglisemia during aripiprazole treatment.

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