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Yıl:2016; Cilt: 9; Sayı: 1>> Özet
Türkiye Klinikleri Psikiyatri Özel Dergisi; 2016;9(1):50-56
Dikkat Eksikliği ve Hiperaktivite Bozukluğunun Genetiği
ANİ Kenar, H Herken
Pamukkale Üniversitesi, Denizli
Dikkat eksikliği hiperaktivite bozukluğu (DEHB) genetik ağırlığı en yüksek psikiyatrik bozukluklardan birisidir. Dikkat eksikliği hiperaktivite bozukluğunda genetik geçiş aile çalışmaları, evlat edinme, ikiz çalışmaları ve moleküler genetik çalışmalar (bağlantı (linkage) ve ilişkilendirme (association) çalışmaları) ile araştırılmıştır. Son yıllarda ise tüm genomun incelendiği ilişkilendirme çalışmaları (GWAS), kopya sayısı değişiklikleri çalışmaları (CNV), farmakogenetik çalışmaları içeren daha ileri genetik araştırmalardan söz edilmektedir. Bu makalede DEHB?nin genetiği ve bununla ilgili araştırmaların gözden geçirilmesi amaçlanmıştır.
Genetics of Attention Deficit Hyperactivity Disorder
Attention deficit hyperactivity disorder (ADHD) is one of the most genetically loaded psychiatric disorders. Genetic inheritance in ADHD is studied by family studies, adoption and twin studies, and molecular genetic studies (linkage and association studies). Recently, advanced genetic studies are discussed including genome wide association studies, copy number variation studies and pharmacogenetic studies. In this study, it is aimed to review genetics of ADHD and studies regarding it.

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