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Yıl:2015; Cilt: 52; Sayı: 3>> Özet
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Nöropsikiyatri Arşivi; 2015;52(3):233-239
İlaç Aşırı Kullanımı Baş Ağrısı Olan Hastalarda Yaşam Olayları ve Yaşam Kalitesi Arasındaki İlişki
E Altıntaş, BK Göksel, N Taşkıntuna, Ç Sarıtürk
Başkent Üniversitesi, Ankara
Amaç: Bu araştırmada ilaç aşırı kullanımı baş ağrısı (İAKB) olan hastalarda stresli yaşam olaylarının çeşidi ve sayısı ile yaşam kalitesi arasındaki ilişkiyi ve stresli yaşam olaylarının baş ağrısının kronikleşmesi ve ilaç aşırı kullanımı haline gelmesinde etkili olup olmadığını belirlemeyi hedefledik. Yöntem: Çalışmaya Uluslararası Baş Ağrısı Derneği’nin (UABD) baş ağrısı kriterlerini karşılayan, yaşları 15-65 arasında olan 114 hasta dahil edildi. Hastalar UABD’nin yeniden düzenlenmiş 2004 kriterlerine göre üç gruba ayrıldı; İAKB(n=64), kronik migren (n=25), epizodik migren (n=25). Ayrıntılı klinik ve sosyo-demografik veriler kaydedildi. Ayırıcı tanı için nörolojik ve fizik muayeneleri yapıldı. Hastalara DSM-IV için Yapılandırılmış Klinik Görüşme Ölçeği (SCID-I), Beck Anksiyete Ölçeği, Beck Depresyon Ölçeği, Kısa Form-36 (KF-36), yaşam olayları listesi uygulandı. Ölçek puanları istatistiksel olarak karşılaştırıldı. Bulgular: İAKB ve Epizodik Migren grupları KF-36 ile karşılaştırıldığında, fiziksel rol güçlüğü (p=0,024), ağrı (p=0,0001), genel sağlık (p=0,043), sosyal fonksiyon (p=0,004) alt ölçek puanlarında istatistiksel olarak anlamlı bir azalma vardı. İAKB olmayan KM hasta grubunda yaşam olay sayısı ile hastalığın kronik olma süresi arasında istatistiksel olarak anlamlı bir ilişki vardı (p=0,027). Ayrıca ailesel stresli yaşam olayları ile yaşam kalitesinin ağrı alt ölçek puanları arasında istatistiksel olarak anlamlı bir ilişki vardı (p=0,038). Sonuç: Bu çalışma, stresli yaşam olaylarının İAKB olan hasta grubunda yaşam kalitesini bozduğunu göstermektedir. Stresli yaşam olay sayısının, baş ağrısının kronik hale gelmesinde etkili olduğu bulunmuştur.
Correlation Between Life Events and Quality of Life in Patients with Medication-Overuse Headache
Introduction: The present study aimed to determine (a) the correlation between type and number of stressful life events and quality of life in patients with medication-overuse headache (MOH) and (b) whether stressful life events could be attributed to medication overuse and the conversion of headache to a chronic type. Methods: The present study included 114 patients aged between 15 and 65 years who met the criteria for headache classification of International Headache Society (IHS). The patients were divided into three groups according to the revised 2004 IHS classification; MOH (n=64), chronic migraine (n=25) and episodic migraine (n=25). Detailed data on clinical and sociodemographic characteristics were recorded. Neurological and physical examinations were performed for differential diagnosis. The patients underwent structured clinical interviews for DSM-IV Inventory (SCID-I), Beck Anxiety Inventory, Beck Depression Inventory, Short Form-36 (SF-36) and Life Events List. Scores of these inventories were statistically compared. Results: Comparing MOH group with episodic migraine group via SF-36, statistically significant decreases were observed in the subscales of physical role limitation (p=0.024), pain (p=0.0001), general health (p=0.043) and social functioning (p=0.004). There was a statistically significant correlation between the number of life events and the time the disease became chronic in the patient group with non-MOH chronic migraine (p=0.027). Moreover, a statistically significant correlation was observed between stressful family life events and the body pain subscale of quality of life scale (p=0.038). Conclusion: The present study demonstrates that stressful life events impair quality of life in patients with MOH. It was also found that number of stressful life events could be attributed to the conversion of headache to a chronic type.

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