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Yıl:2015; Cilt: 2; Sayı: 1>> Özet
TAM METİN
The Journal of Neurobehavioral Sciences; 2015;2(1):29-31
Operasyon Öncesı Fonksiyonel MR'ın Temporal Lobektomi Sonrası Bellek Performansını Yordamada Kullanımı: Sistematık BirDerleme
M Çebi, B Metin, Ç Özkara
Üsküdar Üniversitesi, İstanbul
Epilepsi hastalarının çoğu anteriyor temporal lobektomi (ATL) sonrası bellek performansında düşüş yaşamaktadır. ATL sonrası görülen bellek kaybını araştıran çalışmalar, operasyon sonrası bellek bozukluğunun operasyon öncesinde bellek lateralizasyonu ile yordanabileceğini göstermektedir. Buna göre, operasyon öncesi bellek lateralizasyonunun belirlenmesi epilepsi cerrahisinde önemli role sahiptir. Güncel çalışmalar, beyinde belleği lokalize etmek ve böylece operasyon sonrası bellek performansını yordamada noninvasif ve yinelenebilir bir yöntem olarak fonksiyonel MR görüntülemenin (fmr) invasif ve riskli bir operasyon olan WADA testinin yerine kullanılabileceğini göstermektedir. Bu makalenin amacı, bellek lateralizasyonunda fmr kullanan çalışmaların sonuçlarını özetlemek ve operasyon sonrası bellek bozukluğunu yordamada fmr’ın kullanılabilirliğini gözden geçirmektir.
Functional MRI as a preoperative predictor for memory performance following temporal lobectomy: A systematic review
Most of the patients with temporal lobe epilepsy suffer from memory decline following anterior temporal lobectomy (ATL). Studies examining memory decline following ATL show that post operative memory decline can be predicted in advance through the pre operative determination of memory lateralisation. Therefore, preoperative memory lateralisation plays a crucial role for epileptic surgery. Recent research suggests that instead of WADA test which is known as an invasive and high-risk operation, functional MRI can be used as a non-invasive and repeatable method to lateralize memory in the brain and to predict post operative memory decline. The aim of this article is to review the utility of fmri in prediction of post operative memory decline and to summarize the results of recent memory lateralisation studies using fmri.

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