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Yıl:2002; Cilt: 10; Sayı: 4>> Özet
Psikiyatri Psikoloji Psikofarmakoloji (3P) Dergisi; 2002;10(4):331-340
Alzheimer Tipi Demansta (ATD) algısal ve kavramsal örtük bellek işlevlerinin incelenmesi
B Cangöz, A Akdemir, S Örsel
Ankara SSK Dışkapı Eğt. Araştırma Hastanesi
Amaç: Bu araştırmamın temel amacı Alzheimer Tipi Demanslı (ATD) hastalarda örtük bellek işlevlerini (algısal ve kavramsal) incelemektir. Bu amacı gerçekleştirmek üzere, ATD'lı hasta grubu ile sağlıklı yaşlı grupta bilgi işleme düzeyi (imgeleme,sesli harf sayma, kontrol) ve test türü (kelime kökü tamamlama testi: KKTT, kategori üretim testi: KÜT) değişkenlerinin örtük bellek performansına etkisi test edilmiştir. Yöntem: Araştırmaya NINDS-ADRA ve DSM-IV tanı ölçütlerine göre ATD tanısı almış 20 hasta ile bu grupla yaş, cinsiyet, eğitim düzeyi ve el tercihi açısından eşleştirilmiş 20 sağlıklı yaşlı denek olarak katılmıştır. İstatistik analizlerde 2x2x3 faktörlü son faktörde tekrar ölçümlü ANOVA ve Tukey çoklu karşılaştırma tekniği kullanılmıştır. Bulgular: ATD'lı hasta grubu ile kontrol grubu her iki örtük bellek testinde benzer performans göstermişlerdir. ATD'lı hastalarda farklı bilgi işleme düzeylerini temsil eden koşullar altında, KKTT ve KÜT testi performansı korunmuştur. İmgeleme ve sesli harf sayma koşulları ile kontrol koşulu arasındaki fark istatistiksel olarak anlamlıdır. Tartışma: Araştırma sonuçlarına göre, ATD hastalarında farklı örtük bellek performanslarının incelenmesi korunan örtük bellek işlevlerinden sorumlu kortikal yapılar hakkındaki bilgilerimizi artıracaktır. Bu incelemeler sayesinde hem ATD'da hem de sağlıklı bireylerde örtük bellek işlevlerinin bilişsel ve nöral temellerini açıklamak mümkün olacaktır.

Examination of perceptual and conceptual implicit memory functions in Dementia of Alzheimer Type
Objective: The main purpose of this research is to investigate the implicit memory functions (perceptually and conceptually) in Dementia of Alzheimer Type (DAT). For this direction, present study examined effects of group (DAT vs. control), level-of-processing (imaging vs. counting vowels) and test type (word stem completion test: WSCTvs. category generation test: CGT) variables on implicit memory functions. Method: 20 patients diagnosed as DAT according to NINCDS-ADRDA and DSM-IV diagnosis criteria and 20 healthy elderly (control group) matched according to age, sex, education and manual preference were participated in this study. 2x2x3 factorial ANOVA with repeated measures on the last factor and Tukey post-hoc comparison technique was used for statistical analysis. Results: The DAT patients and control group showed similar performance on two different implicit memory tests. For the DAT patient, performance of WSCT and CGT were intact for words encoded in all level-of-processing condition. Imagery and finding number of vowels conditions were statistically difference than control condition. Discussion: According to the results, the analysis of different implicit memory test performance of DAT patients will increase our knowledge about cortical structures being in charge of preserved implicit memory tests. By the help of studies, it will be possible to define acquainted and neural fundamentals of implicit memory functions in both DAT patients and healthy individuals.

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