Dergi Ara >>
Yıl:2014; Cilt: 17; Sayı: 1>> Özet
Klinik Psikiyatri Dergisi; 2014;17(1):54-58
Tek Doz Kas İçi Haloperidol ve Klorpromazin Uygulanması ile Gelişen Miksödem Koması
S Gündüz, Hİ Aras, FD Geyik
Palandöken Devlet Hastanesi, Erzurum
Tek doz kas içi haloperidol ve klorpromazin uygulanması ile gelişen miksödem koma (MK) olgusu sunulmuştur. Miksödem koma, nadir görülen fakat ölümcül seyir izleyebilen, hipotiroidizmin (HT) en önemli formudur. Olgumuzda, miksödem koma tablosunu tetiklediği bilinen sebeplerin dışlanmasıyla, kas içi uygulanan tedavi olası sebep haline gelmiştir. Literatürde belli antipsikotikler ve antidepresanlar ile gelişen miksödem koma olguları mevcuttur, fakat tek doz kas içi haloperidol ve klorpromazin uygulanması ile gelişen miksödem koma olgusu bildirilmemiştir.
Myxedema Coma Associated with Single Dose Intramuscular Haloperidoland Chlorpromazine Therapy
To describe a case of myxedema coma (MC) associated with single dose of combination of intramuscular haloperidol and chlorpromazine. Myxedema coma, the most significant form of hypothyroidism (HT), is a rare but potentially fatal condition. The known precipitating causes of myxedema coma were ruled out in this patient, which left intramuscular medications as the likely cause. Cases of hypothyroidism caused by certain atypical antipsychotics and antidepressants are found in the literature, but none was reported with single dose of intramuscular haloperidol and chlorpromazine therapy.

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