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Yıl:2005; Cilt: 16; Sayı: 1>> Özet
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Türk Psikiyatri Dergisi; 2005;16(1):13-19
Obsesif Kompulsif Bozuklukta Yaşam Kalitesi: Bilişsel İşlevler ve Klinik Bulgular ile İlişkisi
BB Kıvırcık Akdede, K Alptekin, Y Akvardar, A Kitiş
Amaç: Bu çalışmanın amacı, obsesif kompulsif bozuklukta yaşam kalitesinin sağlıklı bireylerle karşılaştırılması ve yaşam kalitesinin bilişsel işlevler ve klinik bulguların şiddeti ile ilişkisinin araştırılmasıdır.

Yöntem: Bu çalışmaya DSM-IV kriterlerine göre "Obsesif Kompulsif Bozukluk" tanısı almış olan 23 hasta ve 22 sağlıklı birey alındı. Tüm bireylerde yaşam kalitesi (Türkçe Yaşam Kalitesi Ölçeği Kısa Formu) ve bilişsel işlevler değerlendirildi. Hasta grubunda yaşam kalitesinin bilişsel işlevlerle ve klinik bulguların şiddeti ile ilişkisi incelendi. Sağlıklı bireylerde ise yaşam kalitesinin bilişsel işlevler ile ilişkisi araştırıldı.

Bulgular: Hasta ve kontrol grubu yaşam kalitesi yönünden karşılaştırıldığında iki grup arasında anlamlı fark olduğu saptandı (F= 2.60, p= 0.04). Gruplar arasındaki yaşam kalitesindeki bu farklılığın psikolojik ve sosyal alt ölçeklerdeki anlamlı farklılıktan kaynaklandığı saptandı. Hasta grubunda yaşam kalitesi alt ölçek puanları ile bilişsel test (İz Sürme Testi, İşitsel Üçlü Sessiz Harf Sıralaması Testi ve Sayı Dizisi Testi) puanları arasında anlamlı korelasyon saptandı. Ek olarak hasta grubunda yaşam kalitesi puanları ile obsesif-kompulsif belirtilerin şiddeti arasında anlamlı korelasyon saptandı. Kontrol grubunda yaşam kalitesi ile bilişsel testler arasında anlamlı korelasyon saptanmadı.

Tartışma: Bu çalışmada, obsesif kompulsif bozuklukta yaşam kalitesinin sağlıklı bireylere oranla daha düşük olduğu ve yaşam kalitesinin bilişsel işlevler ve obsesif-kompulsif belirtilerin şiddeti ile ilişkili olduğu görülmüştür
Quality of Life in Patients with Obsessive-Compulsive Disorder: Relations with Cognitive Functions and Clinical Symptoms
Objective: To compare quality of life in patients with obsessive-compulsive disorder with that in healthy subjects and to relate quality of life to cognitive functions and the severity of clinical symptoms.

Methods: Twenty-three patients who met DSM-IV criteria for obsessive compulsive disorder and 22 healthy subjects were included in the study. Quality of life (Turkish Quality of Life Scale-Brief Form) and cognitive functions were investigated in all subjects. In the patient group the relation of quality of life to the cognitive functions and to the severity of clinical symptoms and in the control group the relation of quality of life to the cognitive functions was investigated.

Results: The comparison of quality of life between the patient and control groups showed a significant difference (F= 2.60, p= 0.04). The significant differences between the two groups in psychological and social scores were responsible for the overall significant difference. The scores of quality of life were correlated with the scores of the cognitive tests (Trail Making Test, Auditory Consonant Trigram Test and Digit Span Test) and the severity of obsessive-compulsive symptoms.

Conclusion: The present study revealed that quality of life is lower in patients with obsessive-compulsive disorder than in healthy subjects and is related to cognitive functions and the severity of obsessive-compulsive symptoms.


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