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Yıl:2002; Cilt: 39; Sayı: 1>> Özet
TAM METİN
Nöropsikiyatri Arşivi; 2002;39(1):9-19
Obsesif-kompulsif bozukluk ve yeme bozuklukları ilişkisi
MM Demet, EO Taşkın
Celal Bayar Üniversitesi Tıp Fakültesi, Psikiyatri Anabilim Dalı, Manisa
Anoreksiya nervoza (AN) ve obsesif kompulsif bozukluk (OKB) ilişkisi uzun süredir bilinen ve üzerinde halen yoğun olarak çalışılan bir konudur. OKB’nin başka psikiyatrik bozukluklara da yüksek oranlarda eşlik etmesi, OKB ve yeme bozuklukları (YB) arasındaki yüksek komorbidite oranlarının, bu iki bozukluğa özel bir durum olmadığını düşündürmektedir. YB özellikle de AN ile OKB semptomatolojisi arasında genel bir benzerliğin bulunduğu söylenebilir. Tanısal sınıflandırma yaklaşımı ile değerlendirildiğinde YB ve OKB’nin kendilerine özel diğer ölçütler ile farklı kategoriler içinde sınıflandırılmaları bu sendromların tanınmasını ve tanımlanmasını kolaylaştıracaktır. Hem OKB’de YB tanısının bulunması hem de YB’de OKB tanısının bulunması birincil bozukluğun klinik gidiş ve sağaltımını olumsuz yönde etkilemektedir. AN’de Obsesif Kompulsif Kişilik Bozukluğu daha sık görülürken BN’de Borderline Kişilik Bozukluğu ve Narsisistik Nevrozlar sık görülmektedir. AN’de psikopatoloji daha çok obsesyon ve kompulsiyonları andırırken, BN’de daha çok dürtü denetim güçlüğü ya da bozukluğu bulunmaktadır. AN daha çok OKB spektrumuna yakınken BN ise daha çok Dürtü Denetim Bozuklukları’na yakın gibi görülmektedir. Biyolojik olarak, hem YB’nin hem de OKB’nin serotonin işlev bozukluğundan kaynaklandığı söylenebilir. Ancak bu işlev bozuklukları bu bozukluklara özgü değildir. Serotonin değişikliklerinin bozukluklara neden olmaktan çok semptomlarla ilişkili olduğu daha doğru bir yaklaşım gibi görünmektedir.




Relationship Between Obsessive-Compulsive Disorder and Eating Disorder
The relationship between obsessive-compulsive disorder (OCD) and anorexia nervosa (AN) is well documented and widely studied. The high rates of comorbidity between OCD and other psychiatric disorders as well show that the high rates of comorbidity between OCD and ED is not uniqe. It appears that there is a similarity between the symptomatology of ED, particularly between anorexia nervosa (AN), and OCD. In view of descriptive approach, classifying of ED and OCD in different categories according to their own diagnostic criteria will facilitate recognition and description of these syndromes. The comorbidity between ED and OCD negatively effects clinical courses and treatment of primary disorder. Obsessive-compulsive personality disorder is more common in the anorexic patients, but borderline personality disorder and narcissistic neuroses in patients with bulimia nervosa (BN). AN is close to OCD spectrum but BN to Impulse Control Disorders. Biologically, both ED and OCD are linked to serotonin dysfunction. However, this dysfunction is not specific to these disorders. The serotonin dysfunction seems to be related to the symptomatology rather than the etiology of these disorders.


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