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Yıl:2013; Cilt: 23; Sayı: 2>> Özet
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Klinik Psikofarmakoloji Bülteni; 2013;23(2):183-185
Fluoksetin ile hipomanik kayma gelişen bulimik bir hasta: Olgu sunumu
M Ozten, A Erol
Sakarya University Training and Research Hospital, Sakarya
Fluoksetin ile hipomanik kayma gelişen bulimik bir hasta: Olgu sunumu Fluoksetinin mizaç ve anksiyete bozukluklarında antidepresan dozlarda kullanımıyla manik veya hipomanik kaymaya neden olabildiği bilinmektedir. Bulimiya Nervoza (BN)’nın farmakolojik tedavisinde antidepresan etki için kullanılan dozlardan daha yüksek dozlarda fluoksetin kullanılması gerekmektedir. Yüksek doz fluoksetin kullanıldığında manik veya hipomanik kaymaların görülme ihtimali artmaktadır. Mizaç bozukluğu ek hastalığı varlığında BN‘nin fluoksetinle tedavisi manik kayma açısından daha riskli hale gelmektedir. Bipolar bozukluk öyküsü olmayan ve aile öyküsünde de bipolarite saptanmayan BN hastasında 60 mg fluoksetin kullanımı sırasında hipomanik kayma gelişmiştir. BN hastalarında antidepresan ilaç kullanımı, manik kayma riski ve komorbid mizaç bozukluğunun tedaviye direnç oluşturabilmesi vaka bağlamında tartışılmıştır.
Fluoxetine Induced Hypomanic Shift in a Bulimic Patient: Case Report
Fluoxetine induced hypomanic shift in a bulimic patient: case report Use of antidepressant doses of fluoxetine for mood and anxiety disorders is known to cause manic or hypomanic shifts. Fluoxetine should be used at higher doses for pharmacological treatment of bulimia nervosa (BN) than those used for an antidepressant effect. High doses of fluoxetine increase the possibility of manic or hypomanic shifts. In cases of comorbidity of BN and mood disorder, fluoxetine treatment is becomes more risky in terms of the occurrence of a manic shift. During the use of fluoxetine 60 mg by a patient with BN, who had no history of bipolar disorder or family history of bipolarity, a hypomanic shift occurred. A BN patient being treated with an antidepressant, who experienced a manic shift risk and comorbid mood disorder which may cause resistance to treatment, are discussed in this case.

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