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Yıl:2013; Cilt: 23; Sayı: 1>> Özet
TAM METİN
Klinik Psikofarmakoloji Bülteni; 2013;23(1):81-83
Değişken fenomen, dramatik sonuç: Fenitoin toksisitesi olan bir olgu
MS Solanki, K Kumar
Vardhman Mahavir Medical College, New Delhi, India
Değişken fenomen, dramatik sonuç: Fenitoin toksisitesi olan bir olgu Fenitoin birçok ülkede hala yaygın olarak kullanılan bir antiepileptik ilaçtır. Fenitoin’in olağan yan etkileri arasında horizontal nistagmus, ataksi ve bilişsel işlev bozukluğu bildirilmiştir. Bu yazıda, fenitoinin klinik olarak gözden kaçmış yan etkilerine bağlı olarak ortaya çıkan ve davranım bozukluğu şeklinde görülen nadir rastlanan bir fenitoin toksisitesi olgusu sunulmuştur. Fenitoin dozunun azaltılmasıyla yan etkiler ve ikincil davranışsal bulgular düzelmiştir.
Usual Erratic Phenomenon, Dramatic Outcome: A Case Report of Phenytoin Toxicity
Usual erratic phenomenon, dramatic outcome: a case report of phenytoin toxicity Phenytoin is still one of the most commonly used antiepileptic drugs in clinical practice in many countries. It has a range of usual deleterious and erratic side effects, which have been reported previously including horizontal nystagmus, ataxia and cognitive dysfunctions amongst others. Here we report a rare case of phenytoin toxicity presenting dramatically as a behavioral disorder resulting from two underlying primary adverse effects of phenytoin, which were clinically overlooked. Reduction in the dose of phenytoin resulted in remission of side effects as well as the secondary behavioral manifestations.

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