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Yıl:2015; Cilt: 8; Sayı: 1>> Özet
Türkiye Klinikleri Psikiyatri Özel Dergisi; 2015;8(1):38-43
Travma Sonrası Stres Bozukluğu Tedavisinde Farmakolojik Yaklaşımlar
ZB Tatar
Bakırköy Prof.Dr. Mazhar Osman Ruh Sağlığı ve Sinir Hastalıkları Eğitim ve Araştırma Hastanesi, İstanbul
Travma sonrası stres bozukluğu (TSSB) kaza, afet, savaş travması, saldırı, taciz (aile, cinsel, fiziksel ve/veya psikolojik) veya kişinin bütünlüğünü ciddi olarak tehdit eden herhangi bir olaya maruz kalma veya tanık olma sonrası gelişen bir psikiyatrik bozukluktur. Tedavi algoritmaları PTSD tedavisi için farmakoterapiyi ikinci seçenek olarak önermektedir. TSSB'nin yeniden yaşantılama, kaçınma ve aşırı uyarılmışlık gibi ana belirtileri ile işlevsellikte azalma ve psikiyatrik eş tanı gibi ikincil belirtiler tedavi hedeflerini oluşturmaktadır. Farmakoterapi yaklaşımı ilk seçenek olarak seçici serotonin geri alım inhibitörlerini içerir. Trisiklik antidepresanlar, duygudurum düzenleyicileri ve atipik antipsikotik ilaçlar diğer tedavi seçeneklerini oluşturmaktadır. Bu yazıda TSSB'de kullanılan ilaçlar ile TSSB'deki tedavi sürecinin gözden geçirilmesi amaçlanmaktadır.
Pharmacologic Treatment Approaches for Post-traumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is a psychiatric disorder that can develop after experiencing or witnessing a life-threatening event, such as accident, disaster, war trauma, violence or abuse (family, sexual, physical, and/or psychological),or any situation that seriously threatens the integrity of a person. Guidelines recommended drug treatment as a second line treatment for PTSD. The goals in the treatment of PTSD are to reduce core PTSD symptoms, which include persistent re-experiencing of traumatic event, persistent of avoidance of stimuli, hyperarousal and secondary symptoms, which include impaired functioning and psychiatric comorbidity. The first line pharmalogical approach involves the use of the selective serotonin reuptake inhibitors. Tricyclic antidepressants, mood stabilizers and atypical antipsychotics are other treatment options. The aim of this article is to review the pharmacotherapy and treatment process of PTSD.

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