with or without incontinence and increased frequency of voiding and nocturia. Although animal studies have demonstrated the relationship between defective serotonergic neurotransmission and OAB, its etiology is still unclarified. Temperament profiles are hypothesized to be related with serotonergic activity and are studied in many psychosomatic disorders. Thus, we assume that OAB is related with a certain type of temperament. Method: 29 patients, who were admitted to the urology outpatient clinic at Kocaeli University and clinically diagnosed with OAB syndrome, were recruited for the study. Temperament profiles were evaluated with the Temperament Evaluation of Memphis Pisa Paris and San Diego Autoquestionnaire (TEMPS-A). Depressive, hyperthymic, cyclothymic, anxious and irritable temperament scores in patients were compared with those in 25 healthy controls. Results: Patient and control groups were similar in terms of age (p=0.65), sex (p=0.64) and educational level (p=0.90). Anxious temperament scores were higher (p=0.02) and hyperthymic temperament scores were lower (p=0.02) in patients with OAB compared to controls. Depressive, cyclothymic and irritable temperament scores were similar in both groups. There was no significant differences between men and women in both groups in terms of different temperament profile scores. Conclusion: Hypothetically, there might be an association between anxious temperament and OAB syndrome reflecting serotonergic dysfunction. However, OAB syndrome must be considered from the aspect of the interdependence of psychosomatic implications in a narrow sense and psychosomatic dimensions due to the psychological predisposition in the individual case.

ani sikisma hissi, idrar sikliginda artma ve gece sik idrara çikma ile karakterizedir. Hayvan çalismalarinin serotonerjik nörotransmisyondaki bozuklugu AAM ile iliskisini göstermesine ragmen etyoloji hala belirsizdir. Mizaç profillerinin serotonerjik aktivite ile iliskili oldugu iddia edilmis ve birçok psikosomatik bozuklukta çalismalar yapilmistir. Bu bilgiler isiginda hipotezimiz AAM’nin belli bir mizaç türü ile iliskili olabilecegidir. Yöntem: Kocaeli Üniversitesi üroloji poliklinigine basvuran ve AAM tanisi alan 29 hasta çalismaya dahil edildi. Mizaç profilleri TEMPS-A ile degerlendirildi. Depresif, hipertimik, siklotimik, aksiyöz ve iritabl mizaç profilleri 25 saglikli kontrol grubu ile karsilastirildi. Bulgular: Hasta ve çalisma gruplari yas (p=0.65), cinsiyet (p=0.64) ve egitim seviyesi (p=0.90) bakimindan benzerdi. Kontrol grubu ile karsilastirildiginda çalisma grubunda anksiyöz mizaç profilleri daha yüksek (p=0.02), hipertimik mizaç profilleri daha düsük (p=0.02) bulundu. Depresif, siklotimik ve iritabl mizaç profilleri her iki gruta benzer bulundu. Her iki grupta, erkek ve kadin hastalar arasinda farkli mizaç profili puanlarinda anlamli fark saptanmadi. Sonuç: Kuramsal olarak anksiyöz mizaç ile AAM sendromu arasinda serotonerjik disfonksiyonu isaret eden bir iliski olabilir. Bunun yani sira, AAM sendromu, dar anlamda psikosomatik durumlarla iliskili ve olgu bazinda psikolojik hazirlayicilara bagli psikosomatik boyutlar yaklasimiyla dikkate alinmalidir