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Yıl:1998; Cilt: 1; Sayı: 1>> Özet
Klinik Psikiyatri Dergisi; 1998;1(1):31-34
Şizofreni Nörobiyolojisine Kısa Bir Bakış
M Rezaki
Hacettepe Üniversitesi Tıp Fakültesi Psikiyatri Anabilim Dalı, ANKARA
Bu kısa gözden geçirmede belki de psikiyatri tarihinin en hızlı gelişen alanlarından biri olan şizofreni nörobiyolojisi hakkında bir izlenim sunulmaya çalışılmıştır. Şizofreni kliniğinin ortaya çıkışında rol alan temporal loblar ve prefrontal korteks ile ilgili anatomik bulgular kısaca özetlenmiş, ardından şizofrenide nörotransmiter sistemleri ile ilgili bulgulardan dopamin, serotonin ve glutamat üzerinde durularak söz edilmiştir. Bugün bildiklerimiz biraraya getirildiğinde şizofreni patofizyolojisinin anlaşılmasında uzun, ama umut verici bir yolun başında olduğumuz görülmektedir.
Neurobiology of Schizophrenia: A Short Overview
The aim of this short overview is to give a perspective on one of the fastest developing fields of psychiatric history, neurobiology of schizophrenia. A short summary of anatomical findings on prefrontal korteks and temporal lobes in schizophrenia is followed by the findings on neurotransmitter systems, dopamine, serotonin and glutamate in particular. When those findings are put together, it seems that we are at the beginning of a long but hopeful quest for understanding pathophysiology of schizophrenia.

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