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Yıl:2014; Cilt: 25; Sayı: 3>> Özet
TAM METİN
Türk Psikiyatri Dergisi; 2014;25(3):212-214
Parkinson Hastalığında Pramipeksol Kullanımına Bağlı Psikotik Özellikli Mani: Bir Olgu Sunumu
C Meriç, E Pirdoğan, ÖG Toker, A Tekin, B Bakım, S Çelik
Şişli Etfal Eğitim ve Araştırma Hastanesi, İstanbul
Parkinson hastalığı, psikiyatrik belirtilerin sıklıkla eşlik ettiği, hareket bozuklukları ile belirli bir nörodejeneratif hastalıktır. Psikiyatrik belirtiler, hastalığın doğrudan sonucu olarak ortaya çıkabileceği gibi, eşlik eden başka patolojilere veya tedavide kullanılan ilaçlara bağlı olarak da ortaya çıkabilir. Pramipeksol, Parkinson hastalığının tedavisinde kullanılan diğer dopamin agonistleri gibi, merkezi dopaminerjik uyarıma bağlı psikotik ve manik belirtilerin ortaya çıkmasına sebep olabilir. Yazında sık vurgulanmadığı gözlenen dopamin agonisti kullanımına bağlı psikotik özellikli mani, bu yazıda bir olgu üzerinden tartışılacaktır.
Mania with Psychotic Feature Induced by the Use of Pramipexole in Parkinson’s Disease: A Case Report
Parkinson’s disease, a neurodegenerative disorder characterized by movement abnormalities, is frequently complicated by psychiatric syndromes. Psychiatric symptoms may be the direct result of PD, its co-morbid pathologies, or occur as a side effect of its pharmacotherapy. Pramipexole, like other dopamine agonists for treating Parkinson’s disease , has a tendency to induce psychotic and manic symptoms due to central dopaminergic stimulation. In this article, mania with psychotic feature induced by the use of dopamine agonists which is not observed frequently in the literature will be discussed.

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