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Yıl:2013; Cilt: 51; Sayı: 2>> Özet
TAM METİN
Yeni Symposium; 2013;51(2):101-104
Kronik Böbrek Yetmezliği Olan ve Olmayan Diyabetik Hastalarda Nörofizyolojik Değerlendirme
G Benbir, İ Tursun, ME Kızıltan
İstanbul Üniversitesi, İstanbul
Amaç: Periferik polinöropati diyabetes mellitus (DM) ve kronik böbrek yetmezliği (KBY) hastalarında sık olarak karşılaşılan bir komplikasyondur. Çalışmamızda, KBY olan ve olmayan DM hastalarındaki duysal ve motor ileti elektromiyografi (EMG) bulgularının karşılaştırılması amaçlanmıştır. Yöntem: Ardışık 35 DM hastası ile hemodiyaliz tedavi alan ardışık 35 KBY hastası çalışmaya dâhil edilmiş, kontrol grubu olarak da 35 sağlıklı bireyin EMG incelemesi yapılmıştır. Bulgular: Demografik özellikler (yaş, cinsiyet, hastalık süresi) gruplar arasında benzerdi. Tibial (p=0.001) ve peroneal (p=0.022) sinir distal latansları KBY hastalarında daha uzun olarak izlendi. Median ve ulnar motor yanıtları ise iki grup arasında benzerdi. Medial plantar sinir hiç bir KBY hastasında uyarılamazken, sural sinir duysal yanıtları KBY hastalarının ancak %28.5’inde elde edildi; DM hastalarının ise %57.1’sinde sural sinir duysal yanıtları elde edilebildi. Median, ulnar ve radial sinir duysal yanıtları da bu iki grup arasında benzerdi. Tartışma ve Sonuç: Çalışmamızda, KBY gelişen DM hastalarında, KBY gelişmeyen DM hastalarına göre, alt ekstremitelerde belirgin aksonal tipte duysal ağırlıklı mikst tip nöropatik tutulumun daha fazla olduğu gözlemlendi.
Neurophysiological Evaluation of Diabetic Patients with or without Chronic Renal Failure
Purpose: Peripheral polyneuropathy is a common complication of diabetes mellitus (DM) and chronic renal failure (CRF). We aimed to investigate the characteristics of PNP in patients with DM, complicated with CRF or not. Method: Consecutive 35 patients with DM, 35 patients with DM and CRF (under hemodialysis treatment), and 35 healthy controls were enrolled for the electromyographic recordings. Findings: The demographical data was similar in all groups. The latency of tibial (p=0.001) and peroneal (p=0.022) nerves was longer in patients with DM and CRF. Motor responses from the median and ulnar nerves were similar. The medial plantar nerve could not be obtained in any of patients in patients with DM and CRF. The sural nerve could only be evoked in 28.5% of patients in patients with DM and CRF, but in 57.1% of patients in patients with DM. The responses from median, ulnar and radial sensorial nerves were similar. Discussion and Conclusion: Our results showed that the presence of sensory-prominent mixed involvement, axonal involvement, and the involvement of lower extremities are more common in patients with DM complicated with CRF.

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