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Yıl:2013; Cilt: 24; Sayı: 3>> Özet
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Türk Psikiyatri Dergisi; 2013;24(3):213-216
Yıllardır Lityum Kullanan Bir Hastada Polikistik Böbrek Hastalığı
Mİ Atagün, ET Oral, C Sevinç
Namık Kemal Üniv., Tekirdağ.
Lityum duygudurum bozuklukları tedavisinde hala altın standart olarak değerlendirilmektedir. Bu yazıda uzun yıllardır iyi yanıtla lityum kullanan, kreatinin yükselmesi nedeni ile tetkik edilirken polikistik böbrek hastalığı saptanmış olan bir olgu sunulmuştur. Polikistik böbrek hastası olduğu bilinmeden lityum kullanmış olması nedeniyle, istemeden de olsa deneysel olarak polikistik böbrek hastalığında lityum kullanımının etkileri test edilmiştir. Yazıda ayrıca lityumun farmakokinetiği, kist oluşumu ile olası ilişkisi tartışılmıştır.
Polycystic Kidney Disease in a Patient Using Lithium Chronically
Lithium remains to be the gold standard in the treatment of mood disorders. This study presents a case treated with lithium for an extended period with a good response. Following an increase in creatinine levels, further investigation of renal dysfunction revealed polycystic kidney disease. Lithium was used prior to the diagnosis of polycystic kidney disease, resulting in the unique opportunity to examine the effects of lithium on kidneys with polycystic kidney disease. Within this context, this study also discusses the pharmacokinetics of lithium, and its possible relation to cyst formation in polycystic kidney disease.

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