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Yıl:2012; Cilt: 22; Sayı: 3>> Özet
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Klinik Psikofarmakoloji Bülteni; 2012;22(3):275-277
Klozapin çekilmesine bağlı ortaya çıkan katatoni: Bir olgu sunumu
C Cerit, B Tüzün, E Akpınar, E Sahan
Kocaeli Üniv. Tıp Fak.
Katatoni şizofreninin bir alt tipi olmakla beraber katatonik tablolar bir çok farklı tıbbi durumda da karşımıza çıkabilmektedir. Klozapin çekilmesine bağlı ortaya çıkan katatoni tablosuyla ilgili az sayıda vaka bildirimi mevcuttur. Bu çalışmada klozapin kullanımını bıraktıktan beş gün sonra katatoni tablosuyla hastaneye başvuran 46 yaşında bir erkek hasta sunulmuştur. Hastanın 30 yıllık bilinen şizofreni tanısı olup rezidüel şizofreni tanısıyla 10 yıldır düzenli şekilde klozapin kullanmaktaydı. Onbir seans EKT uygulamasından fayda görmeyen hastaya klozapin başlanmasından sonra hızlı bir iyileşme gözlendi. Şizofreni hastalarında başka sebeplere bağlı olarak ortaya çıkan katatonik tablolar tanı karmaşasına ve dolayısıyla tedavide aksamalara yol açabileceğinden bu tip klinik durumların tanınması önemlidir.
Clozapine Withdrawal Catatonia Refractory to ECT: A Case Report
Although catatonia is defined as a subtype of schizophrenia it may occur due to various medical conditions. Catatonic states associated with clozapine withdrawal have been described in a few cases. In this case report, a 46 [year] old man admitted to hospital in a catatonic state five days after discontinuing clozapine is presented. The patient has been diagnosed with residual schizophrenia for 30 [year]s and he has been well maintained on clozapine for 10 [year]s. The catatonia did not respond to ECT after 11 sessions but improved rapidly with the administration of clozapine. Catatonic states due to other etiological causes may present diagnostic and therapeutic difficulties in patients with schizophrenia. The importance of identifying such clinical conditions is underlined.

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