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Yıl:2011; Cilt: 21; Sayı: 2>> Özet
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Klinik Psikofarmakoloji Bülteni; 2011;21(2):156-160
Genç kadın hastada essitalopram kullanımına bağlı hiponatremi
O Çalıyurt, S Derici
Trakya Üniv., Edirne
Seçici serotonin geri alım inhibitörleri klinik pratikte gittikçe artan bir kullanım ve güvenli bir yan etki profili göstermektedir. Bununla birlikte özellikle yaşlı ve kadın hastalarda hiponatremi, az rastlanan fakat önemli ve ölümcül olabilen bir seçici serotonin gerialım inhibitörü (SSGİ) yan etkisi olarak öne çıkmaktadır. Bu yazıda literatürdeki en genç essitalopram kullanımına bağlı hiponatremi olgusu sunulmuştur. On yedi yaşında, bayan, Major Depresyon hastasının esitalopram kullanımı ile akut olarak ortaya çıkan hiponatremisinin erken tanısı ve kullandığı antidepresanla ilişkisinin belirlenerek tedavisi bildirilmiştir. Tedavide ilaç kesimi ile sıvı elektrolit desteği sağlanması başarılı bir sonuç sağlamıştır. Sonuç olarak SSGİ kullanımında hiponatremi gelişimi konusunda farkındalığın ve bu olgu sunumu ile bu önemli yan etkinin gençlerde de ortaya çıkabileceğinin bilinmesi klinik pratikte faydalı olacaktır.
Hyponatremia associated with escitalopram use in a young woman
Selective serotonin re-uptake inhibitors have an increased usage in clinical practice and safe side effect profile. Hyponatremia is a rare but important and sometimes fatal side effect of SSRIs especially in elderly woman. In this paper, we report hyponatremia associated with escitalopram use in the youngest female patient in the literature so far. The reported case is a 17 [year] old female patient with Major Depressive Disorder developed acute hyponatremia. In the report we described early diagnosis of her hyponatremia and the connection with her medication. The treatment including cessation of escitalopram and fluid and electrolyte replacement was successful. In conclusion, it is clinically important to be aware of hyponatremia as an important side effect of SSRIs and young patients could also develop hyponatremia.

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