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Yıl:2011; Cilt: 21; Sayı: 1>> Özet
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Klinik Psikofarmakoloji Bülteni; 2011;21(1):64-66
Pregabalin kötüye kullanımı: bir olgu sunumu
I Yargic, FA Ozdemiroglu
İstanbul Üniversitesi İstanbul Tıp Fakültesi
Pregabalin epilepsi, nöropatik ağrı ve yaygın anksiyete bozukluğunun tedavilerinde kullanılan bir gama-aminobutirik asit (GABA) analoğudur. Pregabalin Türkiye'de kontrole tabi ilaçlardan olmamasına karşın kötüye kullanılma potansiyeline sahiptir. Türkiye'de yaygın anksiteye bozukluğu gibi psikiyatrik hastalıkların tedavisi için ruhsatlandırılmış olmadığı için henüz psikiyatri hastaları arasında popüler değildir. 37 yaşında, bipolar bozukluğu ve benzodiyazepin kötüye kullanımı öyküsü olan bir erkek hastada Türkiye'de n ilk pregabalin kötüye kullanımı olgusunu sunuyoruz. Pregabalin benzodiyazepin bağımlılığı tedavisinde de kullanılabiliyor ve başka tedavilere cevap vermeyen anksiyete bozukluklarında pregabalin eklenmesi tedaviyi güçlendirme stratejisi olarak kullanılabiliyor olsa da alkol ya da madde bağımlılığı öyküsü olan hastalarda pregabalin reçete ederken dikkatli olmamız gereklidir
Pregabalin abuse: a case report
Pregabalin is a gamma-amino butyric acid (GABA) analogue used in the treatment of epilepsy, neuropathic pain, and generalized anxiety disorder. Although pregabalin is not a controlled medication in Turkey, it has a potential risk of abuse. It has not been approved for the treatment of psychiatric disorders (such as generalized anxiety disorder) in Turkey, so it is not yet popular as a drug of abuse among psychiatric patients. We report the first case of pregabalin abuse in Turkey in a 37 [year] old male patient who has a history of bipolar disorder and benzodiazepine abuse. In spite of the fact that pregabalin can be used in the treatment of benzodiazepine dependence, and pregabalin augmentation could be beneficial in treatment of anxiety disorders unresponsive to other medications, clinicians should be cautious while using pregabalin in treating patients with a history of drug or alcohol dependence.

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