Dergi Ara >>
Yıl:1986; Cilt: 1; Sayı: 8>> Özet
TAM METİN
Düşünen Adam: Psikiyatri ve Nörolojik Bilimler Dergisi; 1986;1(8):44-48
Uzun Süreli Haloperidol Kullanımında Ortaya Çıkan Ekstrapramidal Sendromlar ve Bunların Tedavilerinde Antikolinerjik İlaçların Yeri
ŞN Erkoç, O Arkonaç
Bakırköy Ruh ve Sinir Hastalıkları Hastanesi
Bu çalışmada, uzun süreli haloperidol kullanan hastalarda ortaya çıkan ekstrapiramidal semptomlar (EPS) ve semptomların tedavisinde antikolinerjik ajanların yeri araştırılmıştır.
En az üç aydır haloperidol ve biperiden kombinasyonu kulllanmakta olan, kronik işlevsel psikozlu 40 hastada; biperiden kesildikten sonra mevcut EPS ların şiddetlendiği, bazı hastalarda
yeni semptomların ortaya çıktığı tesbit edfldi. Biperiden kesüen hastaların 27 sinde (% 65.5) tekrar biperidene başlamak gerekirken, 13 ünde (% 32.5) böyle bir zorunluluk görülmedi.
Extrapyramidal Syndromes Encountered In Chronic Haloperidol Administration: The Usefulness of Anticholineric Medication in Their Management
40
patients
, all chronically psychotic and on haloperidol-biperidene therapy for at least three [month]s were examined. After withdrawal of biperidene, aggravation of pre-existent extrapyramidal syndromes or emergence of new extrapyramidal syndromes was noticed. In 27 patients (% 67.5) readministration of biperidene was necessary to relieve the symptoms, whereas, in 13 patients (% 32.5), no medication was needed.

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