Dergi Ara >>
Yıl:1986; Cilt: 1; Sayı: 8>> Özet
TAM METİN
Düşünen Adam: Psikiyatri ve Nörolojik Bilimler Dergisi; 1986;1(8):24-28
Amitriptilin Tedavisinde EKG Değişiklikler
N Eradamlar, O Arkonaç
Bakırköy Ruh ve Sinir Hastalıkları Hastanesi
Bu çalışma Bakırköy Ruh ve Sinir Hastalıkları Hastanesi servislerinde Aralık 1983-Mayıs 1984 tarihleri arasında, bilinen bir organik hastalığı olmayan Duygulanım bozukluğu (Majör deresyon, distimik bozukluk, atipik depresyon) tesbit edilmiş 30 hastada günde 150 mg. Amitriplin'in kardiovasküler sistem üzerine etkisini EKG aracılığıyla inceleme amacıyla yapılmıştır.
Amitriptüin tedavisi sırasında ortaya çıkan istatistiksel düzeyde anlamlı EKG değişiklikleri olarak sinus taşikardisi ve T dalgası değişiklikleri tesbit edümiştir.
Çalışma sırasında kalp üetim sisteminde ciddi bir bozukluk, miyokart enfarktüsü ve ani ölüm görülmemesi amitriptilinin kardiyak yakınmaları
olmayan depresif hastalarda kardiovasküler sistem bakımından klinik dozlarda güvenle kullanılabileceğini göstermektedir.
In this article we argued EKG disorders at amitriptiline therapy.

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