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Yıl:2009; Cilt: 11; Sayı: 3>> Özet
Türkiye'de Psikiyatri; 2009;11(3):143-147
Bipolar Bozuklukta Obsesif-Kompulsif Bozukluğun Yaygınlığı
Ö Karaçam
Ege Üniversitesi Sağlık, Kültür ve Spor Daire Başkanlığı
Bipolar bozuklukta eş tanıların, ve özellikle de obsesif-kompulsif bozukluğun yaygınlığı, son on beş yıllık
süreç içinde çeşitli araştırmalara konu olmuştur. Hemen tüm çalışmalarda eş tanıların daha erken başlangıç
yaşı, hızlı döngü, zaman içinde daha şiddetli epizodların gelişmesi ve intihar girişimlerinin yüksek oranda
oluşuyla ilişkili olduğunu düşündüren bulgular saptanmıştır. Bu eş tanılar içinde anksiyete bozuklukları ön
plana çıkmaktadır. Panik bozukluğu eş tanısı alan bipolar hastaların bir genetik alt-tipi temsil ediyor olabileceği
yolunda araştırma kanıtları vardır. Obsesif-kompulsif bozukluğun ise özellikle bipolar-II bozukluk ile ilişkili
olduğu ve ortak bir nörobiyolojik yatkınlığı paylaştığı yolunda araştırma verileri vardır.
Prevalence of Obsessive-Compulsive Disorder in Bipolar Disorder
In the last fifteen [year]s, prevalence of the comorbid disorders, specifically obsessive-compulsive disorder in bipolar disorder has been subject
to many studies. Almost all studies suggested that comorbid disorders were related to earlier ages at first onset, rapid cycling, worsening
severity of episodes over time and high rates of suicide attempts. Most prevalent comorbid disorders were anxiety disorders. Some studies
suggested that bipolar patients with comorbid panic disorder represented a genetic subtype. And some studies suggested that obsessivecompulsive
disorder was related to bipolar-II disorder and both disorders shared a common neurobiological predisposition

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