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Yıl:2009; Cilt: 19; Sayı: 1>> Özet
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Klinik Psikofarmakoloji Bülteni; 2009;19(1):55-58
Ketiapin kullanımı sırasında ortaya çıkan sinüs taşikardisi: Üç olgu sunumu
Ç Hocaoğlu, H Hıdıroğlu, G Kandemir
Karadeniz Teknik Üniversitesi Psikiyatri Anabilim Dalı, Trabzon-Türkiye
Ketiapin, yapısı klozapine benzeyen ve çok sayıda reseptörün antagonisti olan dibenzodiazepin türevi bir atipik antipsikotiktir. fiizofreninin uzun dönem tedavisi ve akut alevlenmelerin tedavisinde ketiapin’in plaseboya göre etkinliği randomize çalışmalarda gösterilmiştir. Ketiapin, diğer antipsikotik tedavilere göre genellikle iyi tolere edilmesine rağmen, sedasyon, ortostatik hipotansiyon, antikolinerjik ve metabolik yan etkileri içermektedir. Bu yazıda, ketiapin kullanımı sırasında sinus taşikardisi ortaya çıkan 3 olgu sunulmuştur.
Sinus tachycardia during quetiapine therapy: Three case reports
Quetiapine, a dibenzothiazepine derivative, is an atypical antipsychotic, multireceptor antagonist that has a preclinical profile similar to clozapine. Randomized studies have demonstrated the efficacy of quetiapine relative to placebo in the treatment of acute relapse and the longterm management of schizophrenia. Quetiapine is generally well tolerated relative to other antipsychotic medications, although sedation, orthostatic hypotension, anticholinergic and metabolic side effects were reported. Three patients who developed sinus tachycardia during quetiapine therapy are presented in this case report.

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