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Yıl:2008; Cilt: 45; Sayı: 3>> Özet
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Nöropsikiyatri Arşivi; 2008;45(3):100-102
İnme Sonrası Patolojik Ağlama Tedavisinde Sitalopramın Etkinliği: Bir Olgu Sunumu
Z Öztürk, G Karakuş, L Tamam
Çukurova Üniversitesi Tıp Fakültesi, Psikiyatri Anabilim Dalı, Adana, Türkiye
Patolojik gülme ağlama (PGA); kontrol edilemeyen, duygudurumla uygunsuz ağlama ve gülme epizodları ile karakterize bir durumdur. PGA sıklıkla serebro vasküler hastalık, amyotrofik lateral skleroz ve multiple skleroz’a bağlı bulber veya psödobulber palsi ile ilişkilidir. PGA’nın altında yatan mekanizmanın, serotonerjik sistem disfonksiyonu olduğu ve serotonerjik rafe çekirdeğinin ve bu çekirdeğin bulunduğu hemisferin parsiyel hasarı sonrası bu sendromun geliştiği düşünülmektedir. Tedavisinde başta selektif serotonin geri alım inhibitörleri olmak üzere çeşitli antidepresanlar ve psikotrop ilaçlar kullanılmaktadır. Burada inme sonrasında patolojik ağlama gelişen 67 yaşında bir olgu ve tedavi süreci tartışılmıştır.
The Efficacy of Citalopram in the Treatment of Postsroke Pathological Crying: A Case Report
Pathological laughing and crying (PLC) is characterized by uncontrollable, mood-incongruent laughing and crying episodes. PLC is commonly associated with cerebrovascular diseases, amyotrophic lateral sclerosis and bulbar and pseudobulbar palsy related to multiple sclerosis. The process underlying PLC has been linked with serotonergic system dysfunction and partial injury of the serotonergic raphe nucleus and associated hemisphere. Serotonin reuptake inhibitors are the mainstay of treatment, but other antidepressants and psychotropic drugs have also been used in the treatment of PLC. Here, a 67 [year] old patient with poststroke PLC and the treatment process employed has been presented and discussed.

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