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Yıl:2005; Cilt: 13; Sayı: Ek 2>> Özet
Psikiyatri Psikoloji Psikofarmakoloji (3P) Dergisi; 2005;13(Ek 2):33-37
Reboksetinin Depresyon Dışındaki Kullanım Alanları
E Tufan, Ü Tural
Kocaeli Ü. Tıp Fak. Psikiyatri ABD
Reboksetin etki mekanizması dolayısı ile türünün tek örneği olarak ilgi çekmektedir. Bu yazının amacı reboksetinin lit­eratürde yer alan depresyon dışındaki kullanım alanlarını araştırmak ve gözden geçirmektir.
Günümüze kadar yapılan çalışmalar reboksetin'in panik bozukluğu, dikkat eksikliği/ hiperaktivite bozukluğu (DEHB), parkinson hastalığı ve inme sonrası görülen depresyon, bulimia nervoza, mevsimsel duygudurum bozukluğu, narkolepsi, sosyal fobi, şizofreni, ağrı bozukluğu, cinsel işlev bozuklukları ve madde kullanımında tedavi edici etkisi olabileceği­ni bildirmektedir. Reboksetinin, her ne kadar umut vaat etse de, depresyon dışındaki kullanım alanlarında plasebo kon­trollü çift kör çalışmalara ihtiyaç vardır ve henüz depresyon dışı kullanımı İçin yeterli kanıt yoktur.
Reboxetine Use in Psychiatric Disorders Other Than Depression
Reboxetine has been drawn attention due to its unique mechanism of action. The aim of this paper is to explore and to review of new indications for reboxetine other than depression.
Studies up to date indicate that reboxetine may be helpful in the treatment of panic disorder, attention deficit/ hyperac­tivity disorder (ADHD), depression in Parkinson's disease and stroke patients, bulimia nervosa, sexual dysfunction and disorders of substance abuse.
There is no clear evidence of a new indication for reboxetine other than depression yet; although recent researches are promising, double blind and placebo controlled studies are needed for the new indications of reboxetine.

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