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Yıl:1991; Cilt: 1; Sayı: 2>> Özet
TAM METİN
Klinik Psikofarmakoloji Bülteni; 1991;1(2):8-10
Psikiyatrik Bozuklukların Tedavisinde Karbamazepin
A Verimli
Bakırköy Ruh ve Sinir Hast. Hastanesi, İstanbul
Antikonvulsif olarak bilinen karbamazepin (CBZ) di-ğer antikonvulsanlarla birlikte psikiyatrik ilaç tedavisinde son yıllarda yaygın biçimde ilgi çekmektedir. Yapılan klinik çalışmalar, CBZ'nin etkili bir antimanik ajan olduğunu göstermiştir. Aynı zamanda, lityuma dirençli bipolar bozuklukların proflaksisinde, dirençli depresyonun tedavisinde tek başına ya da ek olarak kullanılması, yan etkilerinin daha az olması nedeni ile önde gelen seçeneklerden birisi olarak kabul edilmektedir. Bu yazıda bu konu ile ilgili klinik çalışmaları gözden geçirdik.
Carbamazepine in the Treatment of Psychiatric Disorders
The use of carbamazepine (CBZ) and related anticonvulsants has evolved in the past decade so that these treatments now represent alternative or adjunctive modalities for the lithium-resistant, bipolar manic-depressive patients. There is substantial evidence that CBZ has acute antimanic effects. Moreover, double-blind studies indicate that CBZ shows a similar magnitude and time course of acute antimanic efficacy to that achived with classical neurolepitcs with a comparable or lesser incidence of side effects. In this article, we have reviewed the clinical studies related to CBZ.

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