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Yıl:2020; Cilt: 33; Sayı: 4>> Özet
TAM METİN
Düşünen Adam: Psikiyatri ve Nörolojik Bilimler Dergisi; 2020;33(4):437-440
Sentetik kannabis kullanımına bağlı oluşan atipik demiyelinizan lezyonlar, vaka sunumu
Z O Acar, A Soysal
Bakirkoy Prof. Mazhar Osman Mental Health and Neurological Diseases Training and Research Hospital, Istanbul
Sentetik kannabinoidler, nörolojik ve psikiyatrik bulgularla ortaya çıkan merkezi sinir sistemi yan etkilerine neden olabilir. Bu vaka sunumunda kafa karışıklığı ile başvuran ve beynin manyetik rezonans görüntülemesinde (MRG), T2 ve FLAIR serilerinde periventriküler ve subkortikal beyaz cevher ve bazal gangliyon hiperintensiteleri saptanan ve kontrastlı serilerde kısmi kontrastlanma gösteren bir hasta sunulmuştur. Sentetik kannabis kullanımı kötüye kullanım öyküsü olan bu hasta yüksek doz metilprednizolon ile tedavi edilmiştir. Bu maddeler hakkındaki bilgi eksikliği nedeniyle sebep oldukları nöropsikiyatrik morbidite ve mortalite tam olarak bilinmemektedir.
Atypical demyelinating lesions due to synthetic cannabinoids: a case report
Synthetic cannabinoids (SCBs) may cause central nervous system side effects associated with neurological and psychiatric findings. We described a patient with SCBs abuse who presented with confusion. Magnetic Resonance Imaging (MRI) of the brain showed periventricular and subcortical white matter and basal ganglia hyperintensities at T2 and fluid-attenuated inversion recovery sequence with partial rim contrast enhancement on T1-weighted MRI with gadolinium. The patient was treated with high dose methylprednisolone. SCBs can cause serious neurological and psychiatric symptoms. Due to lack of knowledge about these drugs, neuropsychiatric morbidity and mortality are not fully understood.

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