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Yıl:2020; Cilt: 33; Sayı: 1>> Özet
TAM METİN
Düşünen Adam: Psikiyatri ve Nörolojik Bilimler Dergisi; 2020;33(1):1-7
Madde kullanım bozuklukları tedavisinde N-asetilsistein
C Evren, I Alniak
Bakirkoy Training and Research Hospital for Psychiatry Neurology and Neurosurgery- İstanbul
N-asetilsistein (NAC), mukolitik özellikleri ile bronkopulmoner bozukluklarda ve asetaminofen aşırı doz tedavisinde klinik etkinliği ile iyi bilinen bir ajandır. Glutamaterjik reseptörlerdeki kritik rolüne ilişkin hayvan çalışmalarından elde edilen güçlü klinik kanıtlar göz önüne alındığında; NAC, umut verici bir tedavi yaklaşımı olarak çeşitli psikiyatrik bozukluklar üzerinde araştırılmıştır. Bu yazıda, NAC'nin özellikleri ve madde kullanım bozuklukları ve diğer psikiyatrik bozukluklardaki yeri kısaca tartışılacaktır
N-acetylcysteine in the treatment of substance use disorders
N-acetylcysteine (NAC) is an agent best known for its clinical efficacy in bronchopulmonary disorders due to its mucolytic properties, and in the treatment of acetaminophen overdose. Given the strong clinical evidence from animal studies of its critical role in regulating glutamatergic receptors, NAC has also been the subject of research related to several psychiatric disorders as a promising treatment approach. This editorial is a brief discussion of the characteristics of NAC and its place in substance use disorders and other psychiatric disorders.

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