Dergi Ara >>
Yıl:2019; Cilt: 32; Sayı: 3>> Özet
TAM METİN
Düşünen Adam: Psikiyatri ve Nörolojik Bilimler Dergisi; 2019;32(3):275-278
Klozapin kullanımına bağlı miyokardit gelişen bir olguda klozapinin yeniden kullanımı
B Koparal, M Kucukkarapinar, İE Ertek
Recep Tayyip Erdoğan Üniversitesi, Rize
Klozapin, tedaviye dirençli şizofrenide etkinliği kanıtlanmış tek antipsikotiktir. Hayatı tehdit edici olabilen bazı yan etkileri kullanımını sınırlamaktadır. Burada klozapin kullanımına bağlı miyokardit gelişen, sonrasında yeniden klozapin kullanılan bir hastayı sunmakyaız. Hasta halen klozapin kullanmaktadır ve 36 ayı aşkın gözlem süresince miyokardit geliştirmemiştir. Miyokardit gelişimi olsa bile klozapini tekrar kullanmak mümkün olabilir ve bu sayede şizofreni hastalarının semptomlarında ve işlevselliğinde düzelme sağlanabilir.
Rechallenge of clozapine in a patient with a history of clozapine-induced myocarditis
Clozapine is the only antipsychotic with proven efficacy in treatment-resistant schizophrenia, but some life-threatening side effects limit its use. Here we report a patient with clozapine-induced myocarditis and successful rechallenge. The patient still uses clozapine and has not developed myocarditis over 36 months of observation. It may be possible to use clozapine even after myocarditis and thus improve symptoms and functionality of schizophrenia patients.

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