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Yıl:2019; Cilt: 6; Sayı: 1>> Özet
TAM METİN
The Journal of Neurobehavioral Sciences; 2019;6(1):28-32
Sosyal anksiyete bozukluğu hastalarında bipolar bozukluk ektanısı atipik depresyon ile ilişkili olabilir mi?
AŞ Tav, TD Berkol, YE Yıldırım, HY Cengel, Z Özarslan, H Erensoy
Dr. Lutfi Kırdar Kartal Hospital, Istanbul,
Sosyal Anksiyete Bozukluğu (SAB) en yaygın görülen psikiyatrik rahatsızlıklardan biri olup başta duygudurum bozuklukları olmak üzere diğer psikiyatrik hastalıklarla ile sıklıkla birlikte görülmektedir. SAB olan kişilerde Major Depresyon (MD) görülme sıklığının yüksek olması her iki hastalığa bağlı antidepresan kullanımına yaygınlığına sebep olmaktadır. SAB’na en sık eşlik eden psikiyatrik rahatsızlık olan MD tanı kılavuzlarında bir alt grubu olarak belirlenen Atipik Depresyonun daha önceki çalışmalarda Anksiyete Bozuklukları ve Bipolar Bozukluk (BPB) ile olan ilişkisi ortaya konulmuştur. Atipik Depresyonun SAB ile de komorbid olarak daha sık görüldüğünü belirten yayınlar olmakla birlikte bu birlikteliğin Atipik Depresyonun tanı kriterlerinden olan “başkaları tarafından kabul görmemeye duyarlılık”ın SAB’ndaki psikopatolojinin temelinde de yer almasının rol oynadığı düşünülmektedir. SAB’na komorbid olarak BPB sıklığındaki yükseklik hastalık seyri ve tedavi düzenlenmesi açısından daha dikkatli olmayı gerektirmektedir. Bu çalışmaya alınan kişiler; Kartal Eğitim ve Araştırma Hastanesi Psikiyatri Polikliniği’ne 2018 yılı içinde, 7 ay boyunca ayaktan takip edilen poliklinik hastaları arasından dosya taraması şeklinde alınmıştır. Çalışmamız retrospektif olarak yapılmıştır. Çalışmaya alınan kişilere, klinik görüşme (SCID-I) ile DSM-IV’e göre Sosyal Anksiyete Bozukluğu tanısı almış 82 kişi dâhil edilmiştir. Çalışmamızda SAB ile BPB birlikteliği araştırılmış olup, depresif epizodların BPB eşlik eden hastalarda daha fazla olmak üzere çoğunlukla Atipik özellik taşıdığı saptanmıştır. SAB-BPB ve Atipik Depresyon ilişkisi ortaya konulmuş olup bu birlikteliğin sebepleri klinik değerlendirmedeki önemi tartışılmıştır.
Can comorbid bipolar disorder be associated with atypical depression in patients with social anxiety disorder?
Social anxiety disorder (SAD) is one of the most common psychiatric disorders and frequently co-exists with other psychiatric conditions, primarily with mood disorders. MD is the most common psychiatric comorbidity in patients with SAD, and the association of anxiety disorders and bipolar disorder with atypical depression, which is included in diagnostic guidelines for MD as a subgroup, has been well established. The present study aims to determine if SAD patients with comorbid atypical depression or bipolar disorder show differences in terms of symptomatology and disease course compared to SAD patients without bipolar disorder. We hypothesize that social phobia patients may have subgroups within themselves and the processes of these subgroups may be different from those of known SAD patients. In this study a retrospective chart review was performed for patients who had applied to the Psychiatry Outpatient Unit, Kartal Research and Training Hospital, during a 7-month period in 2018. The study had a retrospective design. A total of 82 patients diagnosed with Social Anxiety Disorder based on a SCID-I interview for DSM-IV were included in the study. Of the 82 SAD patients, 16 patients (19.5%) had also co-existing BPD. All SAD patients with comorbid BPD had at least one major depressive episode history, while 15 (93.7%) SAD patients with comorbid BPD exhibited atypical features in at least one episode. Thus, we identified an association between SAD/BPD and atypical depression and discussed the importance of this co-occurrence in terms of clinical evaluation.

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