Dergi Ara >>
Yıl:2018; Cilt: 31; Sayı: 3>> Özet
TAM METİN
Düşünen Adam: Psikiyatri ve Nörolojik Bilimler Dergisi; 2018;31(3):320-323
Aripiprazol Parkinsonizm neden olabilir mi? Aripiprazol kaynaklı Parkinsonizmli iki olgu
HU Erkoyun
Cigli Regional Training Hospital, Cigli - Turkey
Aripiprazol ve Parkinsonizm arasındaki ilişki iyi gösterilmemiştir. Hastalarımızın şu anki şikayetleri, sadece aripiprazolün başlatılmasından birkaç hafta sonra başlamıştır. Aripiprazol uygulamasından sonra ekstrapiramidal sendrom (EPS) gelişen iki kadın olguyu sunuyoruz. Bunların hiçbirinde aripiprazol dışında hiç antipsikotik ajan kullanılmamıştır ve EPS bir antikolinerjik ilaç uygulamasından sonra bir haftadan kısa bir sürede kaybolmuştur. Olgularımızdaki şiddetli Parkinsonizm aripiprazol ile ilişkilidir. Raporumuz, aripiprazol ile tedavi edilen hastalarda Parkinson özelliklerinin gelişiminin dikkatli bir şekilde izlenmesi ihtiyacını vurgulamaktadır.
Can aripiprazole cause Parkinsonism? Two cases with aripiprazole-induced Parkinsonism
The association between aripiprazole and Parkinsonism has not been well demonstrated. Our patients’ present complaints started several weeks after the initiation of aripiprazole only. We present two female cases who developed extrapyramidal syndrome (EPS) after administration of aripiprazole. Neither of them had ever used any antipsychotic agent except aripiprazole and the EPS disappeared within less than a week after administration of an anticholinergic drug. The severe Parkinsonism in our cases is associated with aripiprazole. Our report emphasizes the need for careful monitoring for the development of Parkinsonian features in patients treated with aripiprazole.

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