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Yıl:1996; Cilt: 34; Sayı: 3-4>> Özet
TAM METİN
Yeni Symposium; 1996;34(3-4):83-86
İzole Optik Nörit ve Sessiz Beyin Lezyonları İle Ortaya Çıkan Bir Çocukluk Çağı Multipl Sklerozu
H Tireli, S Baybaş, N Yılmaz, Ç İzkara
Bakırköy Ruh ve Sinir Hastalıkları Hastanesi, 2. Nöroloji\r\nKliniği
Santral sinir sistemi tutuluşu olmaksızın izole idiopatik optik nörit (ON), Multipl Sklerozun (MS) ilk bulgusu
olabilir. izole ON'in kesin MS'e dönüşme oranı % 13 ile % 85 arasında değişmektedir. Manyetik rezonans
(MR) görüntülerne MS'1i hastalarda klinik olarak sessiz beyin lezyonlarını belirlemede yüksek hassasiyeti
olan oldukça yeni bir tekniktir.
Çocukluk çağında izole idiopatik ON atağı olan hastamızda MR, klinik olarak sessiz olan üç beyin lezyonu
göstermiştir. Hastanın sonraki izlenmesinde tipik MS klinik bulguları gelişmiştir.
A Childhood Multiple Sclerosis Case
Isolated idiopathic optic neuritis (ON) without evidence of other central nervous system lesion(s) may be
the first manifestation of Multiple Scierosis (MS). The rate of progression from isolated ON to definite MS
has ranged from 13% to 85 %. Magnetic Resonance Imaging (MRI) is a relatively new tecnic with high
sensitivity for detecting clinically silent brain lesions in patients with MS.
In our patient who experience an episode of isolated idiopathic ON during childhood, MR had showed
three lesions of the brain those were clinically silent. She had gone on to develop definite MS during the
follow-up period.

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