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Yıl:2018; Cilt: 19; Sayı: 2>> Özet
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Bağımlılık Dergisi; 2018;19(2):40-44
Elektronik Sigara (E-sigara) Kullanımına Bağlı Zehirlenmeler
G Göney 
Süleyman Demirel Üniversitesi, Isparta
Günümüzde elektronik nikotin taşıyıcı sistemler (ENDS) diğer isimlendirmeleriyle, “kişisel vaporizer”, “vape pen”, “e-nargile” ya da “e-sigara” son yıllarda oldukça popüler hale gelmiştir. Her ne kadar e-sigara likit (e-likit) içeriği nikotin, propilen glikol, gliserol ve gıda aromaları olmak üzere dört ana bileşenden oluşmaktaysa da bu kimyasal maddelere ek olarak e-likit içeriğinde ya da e-sigara buharında Uluslararası Kanser Araştırma Merkezi (IARC) tarafından insanda kanserojen (Grup 1) olarak tanımlanan benzen, etanol, demir, alüminyum, kadmiyum, tütüne özgü nitrozaminler, polisiklik aromatik hidrokarbonlar ve formaldehit gibi toksik kimyasallar da bulunabilmektedir. Ayrıca e-likit içeriği içerdiği meyve ve çikolata aromaları nedeniyle gençler için çekici gelebilmekte ve e-sigaraya olan ilgi de artabilmektedir. Tütün üreticilerine göre e-sigara likiti 6 ve 36 mg /ml arasında değişiklik gösteren konsantrasyonlarda nikotin içermektedir. Nikotinin LD 50 değeri yetişkin bir insan için 0,5 ve 1,0 mg/kg olup düşük LD 50 değeri ile nikotin oldukça toksik bir bileşiktir. 2010 ve 2014 yılları arasında zehir merkezlerine e-sigaraya bağlı zehirlenmeler ile ilgili yapılan aramalarda artış dikkati çekmektedir. Sunulan çalışmada e-sigara kullanımına bağlı zehir merkezi arama sonuçları ve zehirlenme vakaları derlenmiştir. 
Poisoning due to the Use of Electronic Cigarette (E-Cigarette)
E-cigarettes, also called electronic nicotine delivery systems, personal vaporizers, vape pens, e-cigars, e-hookahs or vaping devices, have become increasingly popular in recent years. E-cigarettes are battery-operated devices designed to vaporize a liquid solution of propylene glycol and/or vegetable glycerin in which nicotine or other aromas may be dissolved. According to the International Agency for Research on Cancer (IARC) have shown that e-cigarette contains Group 1 carcinogens such as benzene, ethanol, formaldehyde, iron, alluminium, cadmium, tobacco-specific nitrosamines, polycyclic aromatic hydrocarbons (PAH), and formaldehyde, which can be harmful to humans. Because of the fruit and chocolate flavors inside has increased the number of young people purchasing e-cigarettes. The concentration ratio of nicotine in the liquid content of e-cigarette varies between 6 and 36 mg/mL. The oral LD50 value (lethal dose 50%) of nicotine is 1.0 mg/kg for adult humans. Between 2010 and 2014, the number of calls made to the poison center due to e-cigarette exposure was increased. In a present study provided that case studies and calls were made to the poison centersdue to e-cigarette exposure.

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