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Yıl:2017; Cilt: 10; Sayı: 1>> Özet
Türkiye Klinikleri Psikiyatri Özel Dergisi; 2017;10(1):44-49
Alzheimer Hastalığı'nda Psikiyatrik ve Davranışsal Sorunların Tedavisi
S Çakır
İstanbul Üniversitesi, İstanbul
Alzheimer Hastalığı'nda psikiyatrik ve davranışsal bulgular hastanın ve bakım verenin yaşam kalitesini bozar, kognitif kötüleşmeye, sık hastane yatışlarına neden olur. En sık görülen iki belirti; apati ve depresyon birbiriyle karıştırılabildiğinden ayırıcı tanı dikkatle yapılmalıdır. Antidepresan ilaçlar depresyon tedavisinde kısıtlı etkiye sahipken, apatide etkisizdir. Agresyon ve psikotik belirtilere neden olabilecek fiziksel ektanılar ve çevresel faktörler araştırılmalı, ilaç dışı tedaviler öncelikle düşünülmelidir. Antipsikotik ilaçlar kısa süreli ve dikkatle kullanılmalı, ciddi olabilecek yan etkileri izlenmelidir.
Treatment of Psychiatric and Behavioral Problems of Alzheimer's Disease
Psychiatric and behavioral symptoms of Alzheimer disease deteriorate the quality of patients and caregivers, cause the cognitive decline and hospitalizations. Most common symptoms are apathy and depression, which might be confused and need clear differential diagnosis. Antidepressant drugs are limited effective in treatment of depression whereas ineffective in treatment of apathy. The physical comorbidities, social stressors which may cause the aggression and psychotic symptoms should be assessed and non-pharmacologic treatments should be implemented primarily. Antipsychotic drugs must be used carefully in short term with close monitoring of serious adverse events.

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