Dergi Ara >>
Yıl:2016; Cilt: 17; Sayı: 3>> Özet
TAM METİN
Bağımlılık Dergisi; 2016;17(3):130-134
Sentetik Kannabinoid Reseptör Agonisti Kullanımına Bağlı Nöbet: Olgu Sunumu
M Altıntaş, M Kuru
Erenköy Ruh ve Sinir Hastalıkları Hastanesi, İstanbul
Yaygınlığı her geçen gün artan ve sağlık çalışanlarını yeni problemler ile karşı karşıya bırakan sentetik kannabinoid reseptör agonistleri (SKRA) birçok sistemi etkilemektedir. Günden güne yeni bildirimler ile neden olabilecekleri klinik tablolar daha öngörülür olmaktadır. Bu maddelerin psikiyatrik, nörolojik, kardiyovasküler, renal ve pulmoner sistemi etkileyen ciddi yan etkileri mevcuttur. Son dönemlerde sentetik kannabinoid reseptör agonistlerinin nöbetlere neden olduğuna dair bildirimlerinin sayısı da artmaya başlamıştır. Özellikle acil servislere SKRA’lerinin neden olduğu toksisite nedeniyle getirilen hastalarda hayatı tehdit edebilecek bir seri klinik tablonun olabileceği ve bunlardan birinin de ciddi nöbetler olabileceği ve kimi zaman yoğun bakım takiplerinin gerekebileceği düşünülmektedir. Bu durum SKRA kullanımı sonrasında oluşabilecek potansiyel tehlikeler konusunda tüm klinisyenlerin ve toplumun haberdar ve hazırlıklı olması gerektiğini göstermektedir. Bu olgu sunumunda daha önce nöbet öyküsü olmayan, SKRA entoksikasyonu sonrası ilk epileptik nöbetini geçiren ve nöbetin güçlükle sonlandırıldığı bir olgudan bahsedilmektedir.
Synthetic Cannabinoid Receptor Agonists (SCRAs) Induced Seizure: A Case Report
With an ever-increasing prevalence, exposing new challenges to healthcare personnel, the use of synthetic cannabinoid receptor agonists (SCRAs) affects many systems. Clinical manifestations that may be caused by it become more predictable day by day thanks to increasing number of case reports on this issue. The use of these substances gives rise to serious side effects, which in turn affect psychiatric, neurological, cardiovascular, renal and pulmonary systems. Recently, there are a growing number of reports indicating that SCRAs would lead to seizures. It is considered that notably the patients referred to emergency rooms due to SCRA induced toxicity may be experiencing a series of life-threatening clinical presentations, one of which would probably be seizure, and which may sometimes require intensive care follow-up. This shows that all clinicians and the society should be highly aware of and get prepared for potential hazards to be triggered by use of SCRAs. This report makes mention of a case where a patient without any record of seizure in his medical history, who experienced his first epileptic seizure following SCRAs induced intoxication, and where the seizure was hardly terminated.

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