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Yıl:2016; Cilt: 53; Sayı: 4>> Özet
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Nöropsikiyatri Arşivi; 2016;53(4):328-333
Semptomatik Remisyon Şizofrenide Fonksiyonel Düzelmeyi ve Yaşam Kalitesini Belirler
MH Kokaçya, O Vırıt, ÜS Çöpoğlu, H Savaş, M Arı, B Bahçeci
Mustafa Kemal Üniversitesi, Hatay
Amaç: Şizofreni, kronik gidişli, yaşam kalitesi ve psikososyal işlevleri önemli derecede olumsuz etkileyen bir hastalıktır. Şizofrenide remisyonu değerlendirmek için tanımlanan ölçütlerin hastaların uzun dönem takibinde ve tanısal etkenleri ayırt etmede yararlı olabileceği düşünülmüştür. Bu çalışmada remisyonda olan şizofreni (R-Sch) hastaları ile remisyonda olmayan şizofreni (Non-R-Sch) hastalarının yaşam kalitesi ve işlevselliği karşılaştırılmıştır. Yöntem: 40 R-Sch ve 40 Non-R-Sch toplam 80 hastanın sosyodemografik verileri toplandı ve hastalara Klinik Global İzlenim-Hastalık şiddeti (CGI-S), Pozitif ve Negatif Sendrom Ölçeği (PANSS), Dünya Sağlık Örgütü Yaşam Kalitesi Ölçeği Kısa Formu Türkçe Versiyonu (WHOQOL-BREF-TR) Öl- çeği, Şizofreni Hastaları İçin Yaşam Niteliği Ölçeği (ŞYNÖ), Global İşlevsellik Değerlendirme Ölçeği (GAF) uygulandı. Bulgular: R-Sch grubunda Non-R-Sch gruba göre PANSS’ın toplam ve tüm alt puanları ve CGI-S skorları anlamlı olarak düşük; GAF puanı, ŞYNÖ ve WHOQOL-BREF-TR ölçeğinin tüm alt puanları ise daha yüksekti. Sonuç: Bu çalışma, şizofrenide belirtilerdeki düzelmenin hastanın hayatının tüm alanlarında işlevselliğini ve hayat kalitesini yükselttiğini göstermiştir ki bu bulgu şizofreni tedavisinde amaçlanan fonksiyonel dü- zelmeyi belirleyen en önemli etkenin belirtilerdeki düzelme olduğunu düşündürmektedir
Symptomatic Remission Determines Functional Improvement and Qualityof Life in Schizophrenia
Introduction: Schizophrenia is a chronic illness that negatively affects the quality of life and psychosocial functions. Defined criteria to assess remission in schizophrenia are considered to be useful in the longterm follow-up of patients and in discriminating diagnostic factors. This study investigated the quality of life and functionality in schizophrenia patients in symptomatic remission (R-Sch) and not in remission (NonR-Sch). Methods: Sociodemographic data were collected for 40 R-Sch and 40 Non-R-Sch patients, and the following scales were administered: the Clinical Global Impression-Severity (CGI-S) Scale; Positive and Negative Syndrome Scale (PANSS), World Health Organization Quality of Life Questionnaire-Short Form, Turkish Version (WHOQOL-BREFTR), Quality of Life Scale for Schizophrenia Patients (QLS), and Global Assessment of Functioning Scale (GAF). Results: The total and all subscale scores of PANSS and the CGI-S score were significantly lower in the R-Sch group than in the NonR-Sch group, whereas the GAF scores and all subscales of QLS and WHOQOL-BREF-TR were significantly higher. Conclusion: This study demonstrates that improvement in symptoms in schizophrenia patients improves quality and functionality in all areas of life, suggesting that an improvement in symptoms is the most important determinant of functional recovery in the treatment of schizophrenia.

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