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Yıl:2016; Cilt: 17; Sayı: Ek 3>> Özet
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Anadolu Psikiyatri Dergisi; 2016;17(Ek 3):45-47
Yedi yaşında erkek çocukta fluoksetinin tetiklediği trikotillomani: Olgu sunumu
N Bolat, M Yavuz
Tepecik Eğitim ve Araştırma Hastanesi, İzmir
Trikotillomani (TMN) ciddi saç kaybı ile sonlanan, yineleyici saç çekme davranışı ile karakterize bir ruhsal bozukluktur. Genellikle TMN’de üzerinde durulan ana nörotransmiter serotonin olmasına rağmen, yeni literatür bilgileri TMN patofizyolojisinde dopaminin rolünü güçlü şekilde desteklemektedir. Bu yazıda yedi yaşında fluoksetin tarafından tetiklenen trikotillomanisi olan bir erkek çocuğu sunmaktayız. Fluoksetin tedavisi ile trikotillomani belirtileri arasındaki zamansal ilgi ve fluoksetin bırakıldığında saç yolmanın olmaması göz önünde bulundurulduğunda, saç yolma davranışının fluoksetin tarafından tetiklendiği düşünülmüştür. Serotonin geri alım inhibitörlerinin dopamin artırıcı etkisi bulunmaktadır. TMN’nin fluoksetin tedavisi sonucunda ortaya çıkan dopamin artışına bağlı olduğunu düşünmekteyiz. Bilgilerimize göre sunulan olgu, antidepresan tedavisi sonucu tetiklenen ilk trikotillomani olgusudur.
Fluoxetine induced trichotillomania in a 7-year- old boy: A case report
Trichotillomania (TTM) is a mental disorder characterized by recurrent hair pulling that result in significant hair loss. Traditionally, serotonin has been the principal neurotransmitter implicated in TTM, however, recent literature strongly supports the role of dopamine in the pathophysiology of TTM. Here we describe 7 year old boy who had fluoxetine-induced trichotillomania. According to the temporal association in time between fluoxetine treatment, the symptoms of trichotillomania and the resolution of symptoms in the absence of fluoxetine, hair pulling was likely fluoxetine induced. It is implicated that serotonin reuptake inhibitors may have facilitative effects on dopamine. We suggest that TTM may be the result of dopamine increase due to fluoxetine treatment. To our knowledge this is the first reported case of antidepressant-induced trichotillomania.

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