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Yıl:2016; Cilt: 17; Sayı: Ek 3>> Özet
TAM METİN
Anadolu Psikiyatri Dergisi; 2016;17(Ek 3):8-10
Düşük doz olanzapin kullanımı sonrası gelişen tortikollis ve tedavisi: Bir olgu sunumu
N Gündüz, H Turan, TS Kirkan
Erzurum Bölge Eğitim ve Araştırma Hastanesi, Erzurum
Olanzapin, mezolimbik dopaminerjik yolağı nigrostriyatal dopamin yolağından daha fazla etkileyen ve bu nedenle daha az ekstrapiramidal belirtilere neden olan, psikotik bozuklukların ve duygudurum bozukluklarının tedavisinde kullanılan bir atipik antipsikotiktir. Tardif distoni ise atipik antipsikotik kullanımı sonrasında nadir görülen, sürekli kas kasılması ile giden, ağrılı, kıvrılma hareketleri ile karakterize bir durumdur. Tardif distonide etkin tedavi seçenekleri sınırlıdır. Ayırıcı tanıda akut distoni, nörolojik hastalıklar ve aile öyküsü dışlanmalıdır. Bu yazıda, başka türlü adlandırılamayan psikotik bozukluk tanısıyla, olanzapin 5 mg/gün kullanan, genç kadın hastada gelişen tortikollis tablosu ve tedavisi tartışılmıştır.
Low dose olanzapine induced torticollis and treatment: A case report
Olanzapine is a second generation antipsychotic agent that is used for the treatment of the psychotic disorders and mood disorders. Olanzapine is also known to have greater affinity for mezolimbic dopaminergic pathway than for nigrostriyatal dopamine pathway. As a result olanzapine is associated with significantly fewer extrapyramidal symptoms. Tardive dystonia is a rare side effect of antipsychotic treatment frequently causing twisting painful muscle contractions. Effective treatment choice for tardive dystonia is limited. The clinicians must consider acute dystonia neurological disorders and family history for differential diagnosis. Here we present a rare case of torticollis after 5 mg/day olanzapine treatment in a young female patient with psychotic disorder.

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