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Yıl:2016; Cilt: 3; Sayı: 2>> Özet
TAM METİN
Türk Uyku Tıbbı Dergisi; 2016;3(2):34-38
İnterstisyel Akciğer Hastalığı Hastalarının Uykuda Solunum Bozuklukları ve Obstrüktif Uyku Apne Sendromu Açısından Değerlendirilmesi
P Hancı, AÖ Alpaydın, BO İtil, İ Öztura, C Sevinç, B Baklan
Dokuz Eylül Üniversitesi, İzmir
Amaç: İnterstisyel akciğer hastalığında (İAH) kronik hastalığa bağlı stres, solunum anormallikleri ve tedavi yan etkileri uyku bozukluklarına yatkınlık yaratabilir. Çalışmamızda İAH hastalarında uyku kalitesi ve Obstrüktif uyku apne sendromu (OUAS) sıklığını araştırmayı amaçladık. Gereç ve Yöntem: Merkezimizde İAH nedeniyle izlemde olan 52 hasta çalışmaya alındı. Hastalara Epworth Uykululuk Skoru (EUS) ve Pitsburgh Uyku Kalite İndeksi (PUKİ) uygulandı. Spirometri ve difüzyon testi yapıldı. EUS’yi 10 ve üzerinde olan 27 hastaya polisomnografi (PSG) uygulandı. Bulgular: EUS’ye göre gündüz uykululuğu olan ve olmayan hastalar arasında demografik özellikler, vücut kitle indeksi, spirometri ve difüzyon testi ölçümleri, PUKİ global puanı ve alt bileşenleri açısından farklılık gözlenmedi. Hastaların %44’ünde PUKİ ile uyku kalitesinin kötü olduğu saptandı. Ancak PSG yapılan 27 hastanın PUKİ global puanı ve alt bileşenlerinin apne hipopne indeksi, evre 1 uyku latensi, uyku etkinliği veya noktürnal desatürasyonla ilişki olmadığı bulundu (p>0,05). Evre 1 uyku süresinin arttığı; evre 2-3 ve hızlı göz hareketleri sürelerinin azaldığı izlendi. Noktürnal hipoksemi belirginleştikçe hastaların uyanma sayısının (p=0,000, r=0,698) arttığı izlendi. OUAS 19 hastada (%70) gözlendi. Sonuç: İAH hastalarında gündüz hipoksemisi olmasa da noktürnal hipoksemi ve OUAS olabileceği ve uyku kalitesinin etkilenebileceği gözlendi. İAH hastalarının gündüz uykululuğu ve uykuda solunum bozukluğu açısından değerlendirilmesinin uygun bir yaklaşım olacağı düşünüldü
Evaluation of Sleep Related Breathing Disorders and Obstructive Sleep Apne Syndrome in Interstitial Lung Patients
Objective: Interstitial lung disease (ILD) may create sleep disturbances due to chronic disease-related stress, respiratory abnormalities and adverse effects of treatment. We aimed to determine the quality of sleep in ILD patients, and the incidence of Obstructive sleep apnea syndrome (OSAS) in these patients. Materials and Methods: Taken to this study were 52 patients who were followed up in our center due to ILD. Epworth Sleepiness Scale (ESS) and Pittsburgh Sleep Quality Index (PSQI) were applied to the patients. Spirometry and diffusion test were performed. Polysomnography (PSG) was performed to 27 patients whose ESS were more than or equal to 10. Results: Demographic characteristics, body mass index, spirometry and diffusion measurements, PSQI global score and the sub-components of it didn’t show difference according to ESS daytime sleepiness. Sleep quality of 44% of the patients was determined to be poor by PSQI. PSQI global score and sub-components weren’t correlated with apnea-hypopnea index, stage 1 latency, sleep efficiency and nocturnal desaturation (p>0.05) in 27 patients who underwent PSG. We observed increased stage 1 sleep and decreased stage 2-3 and rapid eye movement sleep. As nocturnal hypoxemia was seen arousals (p=0.000, r=0.698) increased. OSAS was diagnosed in 19 (70%) of subjects. Conclusion: Although ILD patients don’t have daytime hypoxemia; they may have nocturnal hypoxemia and OSAS, which may effect their sleep quality. Therefore ILD patients should be evaluated for daytime sleepiness, and sleep-related breathing disorders.

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