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Yıl:2016; Cilt: 6; Sayı: 3>> Özet
TAM METİN
Journal of Mood Disorders; 2016;6(3):146-149
Kortikosteroide bağlı hipomani gelişen bir çocuğun tedavisinde metilfenidat kullanımı
H Altun, AN Öksüz, Ö Gül
Kahramanmaraş Sütçü İmam Üniversitesi, Kahramanmaraş
Kortikosteroidler, çocuklarda birçok tıbbi rahatsızlığın tedavisinde sıklıkla kullanılmaktadır. Bu ilaçların psikiyatrik yan etkileri nadir değildir. Kortikosteroid tedavisinin en yaygın yan etkileri irritabilite, uyku bozuklukları, emosyonel labilite, davranışsal değişiklikler, anksiyete, depresyon, psikoz, öfori ve hipomani/manidir. Kısa süreli steroid tedavisinin en sık yan etkisinin öfori ve hipomani olduğu ve kronik kullanımda maniden daha çok depresyon görüldüğü bildirilmiştir. Kortikosteroidlerin psikiyatrik yan etkilerinin mekanizması tam olarak açıklanamamıştır. Metilfenidat, dikkat eksikliği hiperaktivite bozukluğu olan çocukların tedavisinde yaygın olarak kullanılmaktadır. Metilfenidat’ın hipomani/mani semptomlarını tetikleyebileceği ya da alevlendirebileceği bazı çalışmalarda bildirilmiştir. Ancak bu çalışmaların aksine, metilfenidatın hipomani/mani tedavisinde faydalı olduğunu gösteren yayınlar da bulunmaktadır. Bu vaka sunumunda dikkat eksikliği hiperaktivite bozukluğu olan ve kortikosteroid kullanımına bağlı hipomani gelişen ve metilfenidat kullanımı ile hipomani semptomları kontrol altına alınan bir çocuk hasta tartışıldı.
Methylphenidate use in the treatment of a child with corticosteroid-induced hypomania
Corticosteroids are frequently used to treat variety of medical conditions in children. Psychiatric adverse events of these drugs are not rare. The most common adverse effects of corticosteroids therapy includes irritability, sleep disturbances, emotional lability, behavioral changes, anxiety, depression, psychosis, euphoria, and hypomania/ mania. Euphoria and hypomania are reported as the most common side effects of short-term corticosteroid therapy and in chronic use depression is observed more frequently than mania. The mechanism of the psychiatric side effects of corticosteroids is unclear. Methylphenidate is commonly used to treat children with attention deficit hyperactivity disorder (ADHD). It is reported in some studies that methylphenidate can trigger or aggravate hypomania/ mania symptoms. However, in contrast to these studies, there exist some other ones that methylphenidate are useful for hypomania treatment. In this case report, a child patient who are subjected to hypomania progression because of attention deficit hyperactivity disorder and the use of corticosteroids, and hypomania symptoms are controlled with the use of methylphenidate is discussed.

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