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Yıl:2013; Cilt: 23; Sayı: 4>> Özet
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Klinik Psikofarmakoloji Bülteni; 2013;23(4):294-304
Paranoid ve non-paranoid şizofrenihastalarında nöropsikolojik değerlendirme
S Çıtak, ET Çakıcı, M Çakıcı, S Köse
Erenköy Training and Research Hospital for Psychiatric and Neurological Diseases, Istanbul
Paranoid ve non-paranoid şizofreni hastalarında nöropsikolojik değerlendirme Amaç: Şizofrenide bilişsel bozulmalar şizofreninin değişik belirti alt tipleriyle bağlantılıdır. Paranoid tip şizofrenide bilişsel işlevlerin daha iyi korunduğu öne sürülmüştür. Bu çalışmada, nöropsikolojik ölçümlerin, paranoid şizofreni hastalarını paranoid olmayanlardan ayrıştırıp ayrıştırmadığının değerlendirilmesi amaçlanmıştır. Yöntemler: Bu çalışmaya DSM-IV ölçütlerine göre 26 paranoid tip ve 27 non-paranoid tip şizofreni tanısı konan hastalar dahil edilmiştir. Ortalama yaş paranoid hastalarda 38.0±9.1, non-paranoid hastalarda 39.8±16.4 idi. Tüm olgulara, dikkat, yürütücü işlevler, bellek, lisan ve karmaşık algısal işleme gibi işlevleri değerlendirmek üzere tasarlanmış bir dizi testten oluşan geniş ölçekli bir nöropsikolojik test bataryası uygulanmıştır. Bulgular: Paranoid tip şizofreni hastalarının, seçici dikkat/ yürütücü işlevler (Stroop Renk Kelime Testi) (F=6.07, p
Neuropsychological Assessment in Patients with Paranoid and Non-Paranoid Schizophrenia
Neuropsychological assessment in patients with paranoid and non-paranoid schizophrenia Objective: Cognitive impairments in schizophrenia are associated with different symptom subtypes of schizophrenia. It has been suggested that cognitive functions in the paranoid type of schizophrenia were better protected. Here, we examine how neuropsychological measures jointly differentiate patients with paranoid schizophrenia from nonparanoid patients. Methods: Fifty-three patients with schizophrenia, 26 paranoid and 27 non-paranoid, were included in the study. The mean age was 38.0±9.1 in the paranoid patients and 39.8±16.4 in the non-paranoid patients. A comprehensive test battery was administered to evaluate a broad range of cognitive functions including attention, executive functions, memory, language, and complex perceptual processing. Results: Patients with paranoid schizophrenia demonstrated higher performance than non-paranoid patients on measures of selective attention/executive function (Stroop Color-Word Interference Test) (F=6.07, p

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