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Yıl:2015; Cilt: 1; Sayı: 5>> Özet
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Literatür Sempozyum; 2015;1(5):48-50
Tedaviye dirençli işitsel hallüsinasyonların tedavisinde transkranyal manyetik uyarım kullanımı: Bir olgu sunumu
GH Sayar, F Turan, A Özçetin, F Katranlı
Üsküdar Üniversitesi, İstanbul
Amaç: Beyin görüntüleme çalışmaları, işitsel hallüsinasyonların en azından bir kısmının, konuşmayı algılama ile ilişkili beyin alanlarının aktivasyonundan kaynaklandığını düşündürür. Düşük frekanslı transkranial manyetik uyarım kortikal aktivasyonda azalma yaratır. Bu olgu bildiriminde, antipsikotik ilaçlar ve elektrokonvülsif tedaviye dirençli kronik işitsel hallüsinasyonları olan, şizofreni tanısı almış 48 yaşında bir erkek hasta sunulmuştur. Yöntem: İşitsel halüsinasyonların tedavisi için sol temporoparietal kortekse 1 Hz % 110 motor eşik değerinde transkranial manyetik uyarım tedavisi ardışık 10 gün uygulandı. Bulgular: Tekrarlayan transkranial manyetik uyarım tedavisi herhangi bir nöropsikolojik bozulma yaratmadan iyi tolere edildi. İyilik hali takip sürecinde en az 16 hafta boyunca devam etti. Sonuç: Sol temporoparietal alana uygulanan düşük frekanslı (1 Hz) transkranial manyetik stimülasyon, inatçı işitsel halüsinasyonların tedavisinde bir seçenek olarak araştırılmalıdır.
Repetitive transcranial magnetic stimulation in treatment of treatment-refractory auditory hallucinations: A case report
Objective: Neuroimaging studies suggest that auditory hallucinations of speech arise, at least in part, from activation of brain areas underlying speech perception. Low-frequency repetitive transcranial magnetic stimulation produces sustained reductions in cortical activation. Method: This case report describes a 48 years old male patient with a diagnosis of schizophrenia with chronic auditory verbal hallucinations that were resistant to antipsychotic medications and electroconvulsive treatment. Findings: One-hertz (1 Hz) transcranial magnetic stimulation was administered over 10 days at 110% motor threshold targeting areas of left temporoparietal cortex. Repetitive transcranial magnetic stimulation was well tolerated, without evidence of neuropsychological impairment. Patient maintained improvement for at least 16 weeks. Conclusion: Left temporoparietal low (1 Hz) repetitive transcranial magnetic stimulation warrants further study as an intervention for auditory hallucinations.

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