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Yıl:2014; Cilt: 4; Sayı: 3>> Özet
TAM METİN
Journal of Mood Disorders; 2014;4(3):126-129
Sibutramin içeren reçetesiz zayıflama ürününün indüklediği ilk manik hecme
MH Kokaçya, M Şahpolat, F Kurhan
Mustafa Kemal Üniversitesi, Hatay
Sibutramin obesite tedavisinde kullanılan serotonin, noradrenalin ve daha zayıf bir şekilde de dopamin geri alımını engelleyen ve birçok psikiyatrik yan etkileri olan bir beta feniletilamindir. Kardiyolojik yan etkileri nedeniyle yasaklanmış olmasına rağmen halen internet üzerinden “Zayıflama hapı” adı altında satışı devam etmektedir. Antidepresanların manik veya hipomanik kaymaya neden olabilecekleri bilinmektedir. Sibutramin, antidepresan özelliğinden dolayı manik veya hipomanik kaymaya neden olabilir. Biz, internetten satın aldığı sibutramin içeren bir zayıflama ilacını kullandıktan hemen sonra ilk kez manik bir hecme geçiren altı ay sonrasında ise servisimize yine manik hecme nedeniyle yatırılan bir adölesanı sunuyoruz.
First manic episode induced by over the counter slimming drug that contains sibutramine
Sibutramine, a serotonin, noradrenalin and to a lesser extent dopamine reuptake inhibitor, is a beta phenyletylamine used in obesity treatment and has many psychiatric side effects. Although, prohibited due to cardiologic side effects, it is still being sold as “Slimming pills” via internet. It is known that antidepressants can cause manic or hypomanic shifts. Since sibutramine has an antidepressant activity it may cause manic or hypomanic shifts. We present an adolescent who had his first manic episode after using sliming pills, which contain sibutramine, and was admitted to our service for his second manic episode 6 months after his first episode.

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